Moyer JA - Search Results

1

New antihistamines: substituted piperazine and piperidine derivatives as novel H1-antagonists.

Abou-Gharbia M, Moyer JA, Nielsen ST, Webb M, Patel U. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1995 Sep 29;38(20):4026-32. doi: 10.1021/jm00020a018. J Med Chem. 1995. PMID: 7562938

2

Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents.

Abou-Gharbia M, Moyer JA, Patel U, Webb M, Schiehser G, Andree T, Haskins JT. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1989 May;32(5):1024-33. doi: 10.1021/jm00125a016. J Med Chem. 1989. PMID: 2565399

3

Antipsychotic activity of substituted gamma-carbolines.

Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1987 Oct;30(10):1818-23. doi: 10.1021/jm00393a023. J Med Chem. 1987. PMID: 2888898

4

Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies.

Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1988 Jul;31(7):1382-92. doi: 10.1021/jm00402a023. J Med Chem. 1988. PMID: 2898533

5

Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents.

Abou-Gharbia MA, Childers WE Jr, Fletcher H, McGaughey G, Patel U, Webb MB, Yardley J, Andree T, Boast C, Kucharik RJ Jr, Marquis K, Morris H, Scerni R, Moyer JA. Abou-Gharbia MA, et al. Among authors: moyer ja. J Med Chem. 1999 Dec 16;42(25):5077-94. doi: 10.1021/jm9806704. J Med Chem. 1999. PMID: 10602693

6

Psychotropic agents: synthesis and antipsychotic activity of substituted beta-carbolines.

Abou-Gharbia M, Patel UR, Moyer JA, Muth EA. Abou-Gharbia M, et al. Among authors: moyer ja. J Med Chem. 1987 Jun;30(6):1100-5. doi: 10.1021/jm00389a022. J Med Chem. 1987. PMID: 2884314

7

Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere.

Kinney WA, Abou-Gharbia M, Garrison DT, Schmid J, Kowal DM, Bramlett DR, Miller TL, Tasse RP, Zaleska MM, Moyer JA. Kinney WA, et al. Among authors: moyer ja. J Med Chem. 1998 Jan 15;41(2):236-46. doi: 10.1021/jm970504g. J Med Chem. 1998. PMID: 9457246

8

Discovery of a highly potent, functionally-selective muscarinic M1 agonist, WAY-132983 using rational drug design and receptor modelling.

Sabb AL, Husbands GM, Tokolics J, Stein RP, Tasse RP, Boast CA, Moyer JA, Abou-Gharbia M. Sabb AL, et al. Among authors: moyer ja. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1895-900. doi: 10.1016/s0960-894x(99)00313-3. Bioorg Med Chem Lett. 1999. PMID: 10450949

9

Design, synthesis, SAR, and biological evaluation of highly potent benzimidazole-spaced phosphono-alpha-amino acid competitive NMDA antagonists of the AP-6 type.

Baudy RB, Fletcher H 3rd, Yardley JP, Zaleska MM, Bramlett DR, Tasse RP, Kowal DM, Katz AH, Moyer JA, Abou-Gharbia M. Baudy RB, et al. Among authors: moyer ja. J Med Chem. 2001 May 10;44(10):1516-29. doi: 10.1021/jm000385w. J Med Chem. 2001. PMID: 11334562

10

The preclinical pharmacological profile of WAY-132983, a potent M1 preferring agonist.

Bartolomeo AC, Morris H, Buccafusco JJ, Kille N, Rosenzweig-Lipson S, Husbands MG, Sabb AL, Abou-Gharbia M, Moyer JA, Boast CA. Bartolomeo AC, et al. Among authors: moyer ja. J Pharmacol Exp Ther. 2000 Feb;292(2):584-96. J Pharmacol Exp Ther. 2000. PMID: 10640295

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