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An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function.
Cuesta-Hernández HN, Contreras J, Soriano-Maldonado P, Sánchez-Wandelmer J, Yeung W, Martín-Hurtado A, Muñoz IG, Kannan N, Llimargas M, Muñoz J, Plaza-Menacho I. Cuesta-Hernández HN, et al. Among authors: munoz ig. Nat Commun. 2023 Oct 17;14(1):6548. doi: 10.1038/s41467-023-41890-7. Nat Commun. 2023. PMID: 37848415 Free PMC article.
Molecular basis of Tousled-Like Kinase 2 activation.
Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G. Mortuza GB, et al. Among authors: munoz ig. Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y. Nat Commun. 2018. PMID: 29955062 Free PMC article.
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.
Compte M, Harwood SL, Muñoz IG, Navarro R, Zonca M, Perez-Chacon G, Erce-Llamazares A, Merino N, Tapia-Galisteo A, Cuesta AM, Mikkelsen K, Caleiras E, Nuñez-Prado N, Aznar MA, Lykkemark S, Martínez-Torrecuadrada J, Melero I, Blanco FJ, Bernardino de la Serna J, Zapata JM, Sanz L, Alvarez-Vallina L. Compte M, et al. Among authors: munoz ig. Nat Commun. 2018 Nov 15;9(1):4809. doi: 10.1038/s41467-018-07195-w. Nat Commun. 2018. PMID: 30442944 Free PMC article.
Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus, an essential component of the divisome machinery.
Martínez-Caballero S, Mahasenan KV, Kim C, Molina R, Feltzer R, Lee M, Bouley R, Hesek D, Fisher JF, Muñoz IG, Chang M, Mobashery S, Hermoso JA. Martínez-Caballero S, et al. Among authors: munoz ig. Comput Struct Biotechnol J. 2021 Sep 17;19:5392-5405. doi: 10.1016/j.csbj.2021.09.018. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34667534 Free PMC article.
41 results