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Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation.
Taliani S, La Motta C, Mugnaini L, Simorini F, Salerno S, Marini AM, Da Settimo F, Cosconati S, Cosimelli B, Greco G, Limongelli V, Marinelli L, Novellino E, Ciampi O, Daniele S, Trincavelli ML, Martini C. Taliani S, et al. Among authors: mugnaini l. J Med Chem. 2010 May 27;53(10):3954-63. doi: 10.1021/jm901785w. J Med Chem. 2010. PMID: 20408530
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: mugnaini l. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells.
Bocci G, Fioravanti A, La Motta C, Orlandi P, Canu B, Di Desidero T, Mugnaini L, Sartini S, Cosconati S, Frati R, Antonelli A, Berti P, Miccoli P, Da Settimo F, Danesi R. Bocci G, et al. Among authors: mugnaini l. Biochem Pharmacol. 2011 Jun 1;81(11):1309-16. doi: 10.1016/j.bcp.2011.03.022. Epub 2011 Apr 1. Biochem Pharmacol. 2011. PMID: 21459081
Sampling protein motion and solvent effect during ligand binding.
Limongelli V, Marinelli L, Cosconati S, La Motta C, Sartini S, Mugnaini L, Da Settimo F, Novellino E, Parrinello M. Limongelli V, et al. Among authors: mugnaini l. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1467-72. doi: 10.1073/pnas.1112181108. Epub 2012 Jan 11. Proc Natl Acad Sci U S A. 2012. PMID: 22238423 Free PMC article.
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.
Antonioli L, Fornai M, Colucci R, Ghisu N, Da Settimo F, Natale G, Kastsiuchenka O, Duranti E, Virdis A, Vassalle C, La Motta C, Mugnaini L, Breschi MC, Blandizzi C, Del Taca M. Antonioli L, et al. Among authors: mugnaini l. J Pharmacol Exp Ther. 2007 Aug;322(2):435-42. doi: 10.1124/jpet.107.122762. Epub 2007 May 8. J Pharmacol Exp Ther. 2007. PMID: 17488880
Diet regimen in the treatment of food allergy.
Bernardini R, Novembre E, Mugnaini L, Vierucci A. Bernardini R, et al. Among authors: mugnaini l. Ann Ist Super Sanita. 1995;31(4):481-8. Ann Ist Super Sanita. 1995. PMID: 8851704 Review.
[Allergy to latex evaluated at an allergology clinic].
Novembre E, Bernardini R, Brizzi I, Bertini G, Mugnaini L, Mezzetti P, Vierucci A. Novembre E, et al. Among authors: mugnaini l. Pediatr Med Chir. 1996 Mar-Apr;18(2):173-6. Pediatr Med Chir. 1996. PMID: 8767580 Italian.
43 results