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451 results

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Page 1
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Panwalkar P, Tamrazi B, Dang D, Chung C, Sweha S, Natarajan SK, Pun M, Bayliss J, Ogrodzinski MP, Pratt D, Mullan B, Hawes D, Yang F, Lu C, Sabari BR, Achreja A, Heon J, Animasahun O, Cieslik M, Dunham C, Yip S, Hukin J, Phillips JJ, Bornhorst M, Griesinger AM, Donson AM, Foreman NK, Garton HJL, Heth J, Muraszko K, Nazarian J, Koschmann C, Jiang L, Filbin MG, Nagrath D, Kool M, Korshunov A, Pfister SM, Gilbertson RJ, Allis CD, Chinnaiyan AM, Lunt SY, Blüml S, Judkins AR, Venneti S. Panwalkar P, et al. Among authors: mullan b. Sci Transl Med. 2021 Oct 6;13(614):eabc0497. doi: 10.1126/scitranslmed.abc0497. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613815 Free PMC article.
Clinically Integrated Sequencing Alters Therapy in Children and Young Adults With High-Risk Glial Brain Tumors.
Koschmann C, Wu YM, Kumar-Sinha C, Lonigro R, Vats P, Kasaian K, Cieslik M, Cao X, Anderson B, Frank K, Zhao L, Prensner JR, Zureick AH, Everett J, Mullan B, Marini B, Camelo-Piragua S, Venneti S, McKeever P, McFadden K, Lieberman AP, Leonard M, Maher CO, Garton H, Muraszko K, Robertson P, Robinson D, Chinnaiyan AM, Mody R. Koschmann C, et al. Among authors: mullan b. JCO Precis Oncol. 2018;2:PO.17.00133. doi: 10.1200/po.17.00133. Epub 2018 May 4. JCO Precis Oncol. 2018. PMID: 32832832 Free PMC article.
Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.
Messinger D, Harris MK, Cummings JR, Thomas C, Yang T, Sweha SR, Woo R, Siddaway R, Burkert M, Stallard S, Qin T, Mullan B, Siada R, Ravindran R, Niculcea M, Dowling AR, Bradin J, Ginn KF, Gener MAH, Dorris K, Vitanza NA, Schmidt SV, Spitzer J, Li J, Filbin MG, Cao X, Castro MG, Lowenstein PR, Mody R, Chinnaiyan A, Desprez PY, McAllister S, Dun MD, Hawkins C, Waszak SM, Venneti S, Koschmann C, Yadav VN. Messinger D, et al. Among authors: mullan b. Neuro Oncol. 2023 Jan 5;25(1):54-67. doi: 10.1093/neuonc/noac141. Neuro Oncol. 2023. PMID: 35605606 Free PMC article.
CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.
Stallard S, Savelieff MG, Wierzbicki K, Mullan B, Miklja Z, Bruzek A, Garcia T, Siada R, Anderson B, Singer BH, Hashizume R, Carcaboso AM, McMurray KQ, Heth J, Muraszko K, Robertson PL, Mody R, Venneti S, Garton H, Koschmann C. Stallard S, et al. Among authors: mullan b. Acta Neuropathol Commun. 2018 Aug 15;6(1):80. doi: 10.1186/s40478-018-0580-7. Acta Neuropathol Commun. 2018. PMID: 30111355 Free PMC article. No abstract available.
Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma.
Miklja Z, Yadav VN, Cartaxo RT, Siada R, Thomas CC, Cummings JR, Mullan B, Stallard S, Paul A, Bruzek AK, Wierzbicki K, Yang T, Garcia T, Wolfe I, Leonard M, Robertson PL, Garton HJ, Wahl DR, Parmar H, Sarkaria JN, Kline C, Mueller S, Nicolaides T, Glasser C, Leary SE, Venneti S, Kumar-Sinha C, Chinnaiyan AM, Mody R, Pai MP, Phoenix TN, Marini BL, Koschmann C. Miklja Z, et al. Among authors: mullan b. J Clin Invest. 2020 Oct 1;130(10):5313-5325. doi: 10.1172/JCI133310. J Clin Invest. 2020. PMID: 32603316 Free PMC article.
Blood-brain barrier-adapted precision medicine therapy for pediatric brain tumors.
Marini BL, Benitez LL, Zureick AH, Salloum R, Gauthier AC, Brown J, Wu YM, Robinson DR, Kumar C, Lonigro R, Vats P, Cao X, Kasaian K, Anderson B, Mullan B, Chandler B, Linzey JR, Camelo-Piragua SI, Venneti S, McKeever PE, McFadden KA, Lieberman AP, Brown N, Shao L, Leonard MAS, Junck L, McKean E, Maher CO, Garton HJL, Muraszko KM, Hervey-Jumper S, Mulcahy-Levy JM, Green A, Hoffman LM, Dorris K, Vitanza NA, Wang J, Schwartz J, Lulla R, Smiley NP, Bornhorst M, Haas-Kogan DA, Robertson PL, Chinnaiyan AM, Mody R, Koschmann C. Marini BL, et al. Among authors: mullan b. Transl Res. 2017 Oct;188:27.e1-27.e14. doi: 10.1016/j.trsl.2017.08.001. Epub 2017 Aug 10. Transl Res. 2017. PMID: 28860053 Free PMC article.
ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.
Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. Qin T, et al. Among authors: mullan b. Cell Rep. 2022 Jan 11;38(2):110216. doi: 10.1016/j.celrep.2021.110216. Cell Rep. 2022. PMID: 35021084 Free PMC article.
Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.
Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi M, Parsons DW, Leary S, Mueller S, Ligon KL, Koschmann C. Miklja Z, et al. Among authors: mullan b. Neuro Oncol. 2019 Aug 5;21(8):968-980. doi: 10.1093/neuonc/noz022. Neuro Oncol. 2019. PMID: 30805642 Free PMC article.
451 results