Muqit MM - Search Results

1

Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog.

Rogerson DT, Sachdeva A, Wang K, Haq T, Kazlauskaite A, Hancock SM, Huguenin-Dezot N, Muqit MM, Fry AM, Bayliss R, Chin JW. Rogerson DT, et al. Among authors: muqit mm. Nat Chem Biol. 2015 Jul;11(7):496-503. doi: 10.1038/nchembio.1823. Epub 2015 Jun 1. Nat Chem Biol. 2015. PMID: 26030730 Free PMC article.

2

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM. Kondapalli C, et al. Among authors: muqit mm. Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080. Open Biol. 2012. PMID: 22724072 Free PMC article.

3

Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity.

Kazlauskaite A, Kelly V, Johnson C, Baillie C, Hastie CJ, Peggie M, Macartney T, Woodroof HI, Alessi DR, Pedrioli PG, Muqit MM. Kazlauskaite A, et al. Among authors: muqit mm. Open Biol. 2014 Mar 19;4(3):130213. doi: 10.1098/rsob.130213. Open Biol. 2014. PMID: 24647965 Free PMC article.

4

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.

Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: muqit mm. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.

5

PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease.

Kazlauskaite A, Muqit MM. Kazlauskaite A, et al. Among authors: muqit mm. FEBS J. 2015 Jan;282(2):215-23. doi: 10.1111/febs.13127. Epub 2014 Nov 20. FEBS J. 2015. PMID: 25345844 Free PMC article. Review.

6

A Versatile Strategy for the Semisynthetic Production of Ser65 Phosphorylated Ubiquitin and Its Biochemical and Structural Characterisation.

Han C, Pao KC, Kazlauskaite A, Muqit MM, Virdee S. Han C, et al. Among authors: muqit mm. Chembiochem. 2015 Jul 27;16(11):1574-9. doi: 10.1002/cbic.201500185. Epub 2015 Jun 18. Chembiochem. 2015. PMID: 26010437 Free PMC article.

7

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM. Kazlauskaite A, et al. Among authors: muqit mm. EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25. EMBO Rep. 2015. PMID: 26116755 Free PMC article.

8

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation.

Pao KC, Stanley M, Han C, Lai YC, Murphy P, Balk K, Wood NT, Corti O, Corvol JC, Muqit MM, Virdee S. Pao KC, et al. Among authors: muqit mm. Nat Chem Biol. 2016 May;12(5):324-31. doi: 10.1038/nchembio.2045. Epub 2016 Mar 7. Nat Chem Biol. 2016. PMID: 26928937 Free PMC article.

9

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells.

Kakade P, Ojha H, Raimi OG, Shaw A, Waddell AD, Ault JR, Burel S, Brockmann K, Kumar A, Ahangar MS, Krysztofinska EM, Macartney T, Bayliss R, Fitzgerald JC, Muqit MMK. Kakade P, et al. Open Biol. 2022 Jan;12(1):210264. doi: 10.1098/rsob.210264. Epub 2022 Jan 19. Open Biol. 2022. PMID: 35042401 Free PMC article.

10

Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations.

Woodroof HI, Pogson JH, Begley M, Cantley LC, Deak M, Campbell DG, van Aalten DM, Whitworth AJ, Alessi DR, Muqit MM. Woodroof HI, et al. Among authors: muqit mm. Open Biol. 2011 Nov;1(3):110012. doi: 10.1098/rsob.110012. Open Biol. 2011. PMID: 22645651 Free PMC article.

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