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Limited oxygen in standard cell culture alters metabolism and function of differentiated cells.
Tan J, Virtue S, Norris DM, Conway OJ, Yang M, Bidault G, Gribben C, Lugtu F, Kamzolas I, Krycer JR, Mills RJ, Liang L, Pereira C, Dale M, Shun-Shion AS, Baird HJ, Horscroft JA, Sowton AP, Ma M, Carobbio S, Petsalaki E, Murray AJ, Gershlick DC, Nathan JA, Hudson JE, Vallier L, Fisher-Wellman KH, Frezza C, Vidal-Puig A, Fazakerley DJ. Tan J, et al. Among authors: murray aj. EMBO J. 2024 Apr 5. doi: 10.1038/s44318-024-00084-7. Online ahead of print. EMBO J. 2024. PMID: 38580776 Free article.
Academic drug discovery: Challenges and opportunities.
Murray AJ, Cox LR, Adcock HV, Roberts RA. Murray AJ, et al. Drug Discov Today. 2024 Apr;29(4):103918. doi: 10.1016/j.drudis.2024.103918. Epub 2024 Feb 14. Drug Discov Today. 2024. PMID: 38360148 Free article.
Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders.
Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, Cowan QT, Bruck PT, Mercader K, Alotaibi M, Long T, Hall JE, Moya EA, Bauk MA, Reeves JJ, Kong MC, Salem RM, Vizcardo-Galindo G, Macarlupu JL, Figueroa-Mujíca R, Bermudez D, Corante N, Gaio E, Fox KP, Salomaa V, Havulinna AS, Murray AJ, Malhotra A, Powel FL, Jain M, Komor AC, Cavalleri GL, Huff CD, Villafuerte FC, Simonson TS. Lawrence ES, et al. Among authors: murray aj. Sci Adv. 2024 Feb 9;10(6):eadj5661. doi: 10.1126/sciadv.adj5661. Epub 2024 Feb 9. Sci Adv. 2024. PMID: 38335297 Free PMC article.
Programming of cardiac metabolism by miR-15b-5p, a miRNA released in cardiac extracellular vesicles following ischemia-reperfusion injury.
Pantaleão LC, Loche E, Fernandez-Twinn DS, Dearden L, Córdova-Casanova A, Osmond C, Salonen MK, Kajantie E, Niu Y, de Almeida-Faria J, Thackray BD, Mikkola TM, Giussani DA, Murray AJ, Bushell M, Eriksson JG, Ozanne SE. Pantaleão LC, et al. Among authors: murray aj. Mol Metab. 2024 Feb;80:101875. doi: 10.1016/j.molmet.2024.101875. Epub 2024 Jan 11. Mol Metab. 2024. PMID: 38218535 Free PMC article.
Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia.
O'Brien KA, Gu W, Houck JA, Holzner LMW, Yung HW, Armstrong JL, Sowton AP, Baxter R, Darwin PM, Toledo-Jaldin L, Lazo-Vega L, Moreno-Aramayo AE, Miranda-Garrido V, Shortt JA, Matarazzo CJ, Yasini H, Burton GJ, Moore LG, Simonson TS, Murray AJ, Julian CG. O'Brien KA, et al. Among authors: murray aj. Hypertension. 2024 Feb;81(2):319-329. doi: 10.1161/HYPERTENSIONAHA.123.21748. Epub 2023 Nov 29. Hypertension. 2024. PMID: 38018457
209 results