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Page 1
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
Schöller E, Marks J, Marchand V, Bruckmann A, Powell CA, Reichold M, Mutti CD, Dettmer K, Feederle R, Hüttelmaier S, Helm M, Oefner P, Minczuk M, Motorin Y, Hafner M, Meister G. Schöller E, et al. Among authors: mutti cd. Mol Cell. 2021 Dec 2;81(23):4810-4825.e12. doi: 10.1016/j.molcel.2021.10.018. Epub 2021 Nov 12. Mol Cell. 2021. PMID: 34774131 Free article.
The human mitochondrial genome contains a second light strand promoter.
Tan BG, Mutti CD, Shi Y, Xie X, Zhu X, Silva-Pinheiro P, Menger KE, Díaz-Maldonado H, Wei W, Nicholls TJ, Chinnery PF, Minczuk M, Falkenberg M, Gustafsson CM. Tan BG, et al. Among authors: mutti cd. Mol Cell. 2022 Oct 6;82(19):3646-3660.e9. doi: 10.1016/j.molcel.2022.08.011. Epub 2022 Aug 30. Mol Cell. 2022. PMID: 36044900 Free article.
A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly.
Di Nottia M, Marchese M, Verrigni D, Mutti CD, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R. Di Nottia M, et al. Among authors: mutti cd. Neurobiol Dis. 2020 Jul;141:104880. doi: 10.1016/j.nbd.2020.104880. Epub 2020 Apr 25. Neurobiol Dis. 2020. PMID: 32344152 Free article.