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Human endogenous retrovirus-K contributes to motor neuron disease.
Li W, Lee MH, Henderson L, Tyagi R, Bachani M, Steiner J, Campanac E, Hoffman DA, von Geldern G, Johnson K, Maric D, Morris HD, Lentz M, Pak K, Mammen A, Ostrow L, Rothstein J, Nath A. Li W, et al. Among authors: bachani m. Sci Transl Med. 2015 Sep 30;7(307):307ra153. doi: 10.1126/scitranslmed.aac8201. Sci Transl Med. 2015. PMID: 26424568 Free PMC article.
Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic.
Steiner JP, Bachani M, Malik N, DeMarino C, Li W, Sampson K, Lee MH, Kowalak J, Bhaskar M, Doucet-O'Hare T, Garcia-Montojo M, Cowen M, Smith B, Reoma LB, Medina J, Brunel J, Pierquin J, Charvet B, Perron H, Nath A. Steiner JP, et al. Among authors: bachani m. Ann Neurol. 2022 Oct;92(4):545-561. doi: 10.1002/ana.26452. Epub 2022 Jul 30. Ann Neurol. 2022. PMID: 35801347 Free PMC article.
Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor.
Toodle V, Lee MH, Bachani M, Ruffin A, Vivekanandhan S, Malik N, Wang T, Johnson TP, Nath A, Steiner JP. Toodle V, et al. Among authors: bachani m. Neurotherapeutics. 2022 Jul;19(4):1313-1328. doi: 10.1007/s13311-022-01265-0. Epub 2022 Jul 13. Neurotherapeutics. 2022. PMID: 35831747 Free PMC article.
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Abrams RPM, Yasgar A, Teramoto T, Lee MH, Dorjsuren D, Eastman RT, Malik N, Zakharov AV, Li W, Bachani M, Brimacombe K, Steiner JP, Hall MD, Balasubramanian A, Jadhav A, Padmanabhan R, Simeonov A, Nath A. Abrams RPM, et al. Among authors: bachani m. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31365-31375. doi: 10.1073/pnas.2005463117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229545 Free PMC article.