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A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia.
Yu L, Lemay P, Ludlow A, Guyot MC, Jones M, Mohamed FF, Saroya GA, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, Kaartinen V, Rothstein TL, Justice MJ, Kibar Z, Singh SA. Yu L, et al. Among authors: myers g. Blood Adv. 2021 Oct 26;5(20):4167-4178. doi: 10.1182/bloodadvances.2021004658. Blood Adv. 2021. PMID: 34464976 Free PMC article.
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.
Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS. Mahamud MR, et al. Among authors: myers g. Development. 2019 Nov 5;146(21):dev184218. doi: 10.1242/dev.184218. Development. 2019. PMID: 31582413 Free PMC article.
Small molecule therapeutics to treat the β-globinopathies.
Yu L, Myers G, Engel JD. Yu L, et al. Among authors: myers g. Curr Opin Hematol. 2020 May;27(3):129-140. doi: 10.1097/MOH.0000000000000579. Curr Opin Hematol. 2020. PMID: 32167945 Free PMC article. Review.
An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim KC, Engel JD. Yu L, et al. Among authors: myers g. Blood. 2021 Nov 4;138(18):1691-1704. doi: 10.1182/blood.2021011682. Blood. 2021. PMID: 34324630 Free PMC article.
Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Yu L, Myers G, Schneider E, Wang Y, Mathews R, Lim KC, Siemieniak D, Tang V, Ginsburg D, Balbin-Cuesta G, Singh SA, Phuwakanjana P, Jearawiriyapaisarn N, Khoriaty R, Engel JD. Yu L, et al. Among authors: myers g. Blood Adv. 2022 Jun 14;6(11):3280-3285. doi: 10.1182/bloodadvances.2021006802. Blood Adv. 2022. PMID: 35240686 Free PMC article.
1,153 results