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Page 1
Tumor suppressor BTG1 limits activation of BCL6 expression downstream of ETV6-RUNX1.
Exp Hematol. 2018 Apr;60:57-62.e3. doi: 10.1016/j.exphem.2018.01.006. Epub 2018 Feb 8.
Exp Hematol. 2018.
PMID: 29408281
Free article.
Presence of mutant p53 increases stem cell frequency and is associated with reduced binding to classic TP53 binding sites in cell lines and primary AMLs.
Gerritsen M, Hilgendorf S, Yi G, Wierenga ATJ, Schuringa JJ, Martens JHA, Vellenga E.
Gerritsen M, et al.
Exp Hematol. 2022 Jun;110:39-46. doi: 10.1016/j.exphem.2022.03.007. Epub 2022 Mar 18.
Exp Hematol. 2022.
PMID: 35315319
Free article.
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Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.
In't Hout FEM, Gerritsen M, Bullinger L, Van der Reijden BA, Huls G, Vellenga E, Jansen JH.
In't Hout FEM, et al. Among authors: gerritsen m.
Haematologica. 2020 Sep 1;105(9):e454-457. doi: 10.3324/haematol.2019.232827.
Haematologica. 2020.
PMID: 33054062
Free PMC article.
No abstract available.
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Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern.
Berger G, Gerritsen M, Yi G, Koorenhof-Scheele TN, Kroeze LI, Stevens-Kroef M, Yoshida K, Shiraishi Y, van den Berg E, Schepers H, Huls G, Mulder AB, Ogawa S, Martens JHA, Jansen JH, Vellenga E.
Berger G, et al. Among authors: gerritsen m.
Blood Adv. 2019 Oct 22;3(20):3111-3122. doi: 10.1182/bloodadvances.2019000518.
Blood Adv. 2019.
PMID: 31648334
Free PMC article.
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RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLs.
Gerritsen M, Yi G, Tijchon E, Kuster J, Schuringa JJ, Martens JHA, Vellenga E.
Gerritsen M, et al.
Blood Adv. 2019 Feb 12;3(3):320-332. doi: 10.1182/bloodadvances.2018024422.
Blood Adv. 2019.
PMID: 30709863
Free PMC article.
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CD34+ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax.
Mattes K, Gerritsen M, Folkerts H, Geugien M, van den Heuvel FA, Svendsen AF, Yi G, Martens JHA, Vellenga E.
Mattes K, et al. Among authors: gerritsen m.
Haematologica. 2020 Aug;105(8):e399-e403. doi: 10.3324/haematol.2019.229997. Epub 2019 Nov 14.
Haematologica. 2020.
PMID: 31727766
Free PMC article.
No abstract available.
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