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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
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1981 1
1982 1
1983 2
1984 3
1985 3
1986 10
1987 8
1988 8
1989 13
1990 15
1991 9
1992 26
1993 15
1994 15
1995 26
1996 26
1997 36
1998 37
1999 36
2000 24
2001 39
2002 38
2003 47
2004 42
2005 57
2006 49
2007 54
2008 55
2009 48
2010 54
2011 65
2012 49
2013 57
2014 46
2015 70
2016 57
2017 39
2018 41
2019 44
2020 45
2021 45
2022 35
2023 33
2024 11

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Page 1
Did you mean n kohn[Author] (1,443 results)?
Identification of inflamed-phenotype of small cell lung cancer leading to the efficacy of anti-PD-L1 antibody and chemotherapy.
Shirasawa M, Yoshida T, Shiraishi K, Takigami A, Takayanagi D, Imabayashi T, Matsumoto Y, Masuda K, Shinno Y, Okuma Y, Goto Y, Horinouchi H, Yotsukura M, Yoshida Y, Nakagawa K, Tsuchida T, Hamamoto R, Yamamoto N, Motoi N, Kohno T, Watanabe SI, Ohe Y. Shirasawa M, et al. Among authors: kohno t. Lung Cancer. 2023 May;179:107183. doi: 10.1016/j.lungcan.2023.107183. Epub 2023 Mar 25. Lung Cancer. 2023. PMID: 37037178
The association between the efficacy of ACE therapy, pathological subtypes, and TIL status was evaluated in the ES-SCLC cohort. RESULTS: The LS-SCLC cohort (N = 48) was classified into four SCLC subtypes (ASCL1 + NEUROD1 [SCLC-A + N, N = 17], POU2F3 [SCLC-P, …
The association between the efficacy of ACE therapy, pathological subtypes, and TIL status was evaluated in the ES-SCLC cohort. RESULTS: The …
Clinicopathological characteristics and molecular analysis of lung cancer associated with ciliated muconodular papillary tumor/bronchiolar adenoma.
Higashiyama M, Motoi N, Yotsukura M, Yoshida Y, Nakagawa K, Yagishita S, Shirasawa M, Yoshida T, Shiraishi K, Kohno T, Ohe Y, Watanabe SI. Higashiyama M, et al. Among authors: kohno t. Pathol Int. 2023 May;73(5):188-197. doi: 10.1111/pin.13316. Epub 2023 Mar 9. Pathol Int. 2023. PMID: 36896472
We identified eight LCCM (0.4%) from the resected Stage 0-III primary LC (n = 1945). The LCCM cohort was male-dominant (n = 8), elderly (median 72 years old), and most were smokers (n = 6). ...One exceptional case was invasive mucinous adenocarcinoma harborin …
We identified eight LCCM (0.4%) from the resected Stage 0-III primary LC (n = 1945). The LCCM cohort was male-dominant (n = 8) …
Roles for N-glycosylation in the dynamics of Edg-1/S1P1 in sphingosine 1-phosphate-stimulated cells.
Kohno T, Igarashi Y. Kohno T, et al. Glycoconj J. 2004;21(8-9):497-501. doi: 10.1007/s10719-004-5540-8. Glycoconj J. 2004. PMID: 15750791 Review.
Our recent novel studies established that Edg-1/S1P1 is glycosylated in its N-terminal extracellular portion and further identified the specific glycosylation site as asparagine 30. We also demonstrated that the structure of the N-terminal ectodomain of Edg-1/S1P1 a …
Our recent novel studies established that Edg-1/S1P1 is glycosylated in its N-terminal extracellular portion and further identified t …
Cognition during active methamphetamine use versus remission.
Huckans M, Boyd S, Moncrief G, Hantke N, Winters B, Shirley K, Sano E, McCready H, Dennis L, Kohno M, Hoffman W, Loftis JM. Huckans M, et al. Among authors: kohno m. J Clin Exp Neuropsychol. 2021 Aug;43(6):599-610. doi: 10.1080/13803395.2021.1976734. Epub 2021 Oct 6. J Clin Exp Neuropsychol. 2021. PMID: 34612792 Free PMC article.
OBJECTIVE: To evaluate whether cognitive performance in adults with active methamphetamine use (MA-ACT) differs from cognitive performance in adults in remission from MA use disorder (MA-REM) and adults without a history of substance use disorder (CTLs). METHOD: MA-ACT (n …
OBJECTIVE: To evaluate whether cognitive performance in adults with active methamphetamine use (MA-ACT) differs from cognitive performance i …
Treatment patterns and trajectories in patients after acute heart failure hospitalization.
Nakamaru R, Shiraishi Y, Kohno T, Nagatomo Y, Akiyama H, Motoya Y, Fukui M, Yajima T, Yoshikawa T, Kohsaka S. Nakamaru R, et al. Among authors: kohno t. ESC Heart Fail. 2024 Apr;11(2):692-701. doi: 10.1002/ehf2.14635. Epub 2023 Dec 14. ESC Heart Fail. 2024. PMID: 38098210 Free PMC article.
We categorized them into five groups based on LVEF changes: HF with unchanged-preserved EF [HFunc-pEF (EF 50%); N = 527, 32.2%], unchanged-mildly reduced EF [HFunc-mrEF (EF 41-49%); N = 86, 5.3%], unchanged-reduced EF [HFunc-rEF (EF 40%); N = 377, 23.0%], wor …
We categorized them into five groups based on LVEF changes: HF with unchanged-preserved EF [HFunc-pEF (EF 50%); N = 527, 32.2%], unch …
Vascular dopamine-I receptors and atherosclerosis.
Yasunari K, Kohno M, Kano H, Yokokawa K, Minami M, Yoshikawa J. Yasunari K, et al. Among authors: kohno m. J Atheroscler Thromb. 1997;4(2):59-64. doi: 10.5551/jat1994.4.59. J Atheroscler Thromb. 1997. PMID: 9638515 Review.
The actions are blocked by a specific protein kinase A (PKA) inhibitor N-[2-(p-bromocinnamylamino) ethyl]-5-isoquinoline-sulfonamide (H 89), but are not blocked by its negative control, N-[2-(N-formyl-p-chlorocinnamylamino) ethyl]-5-isoquinoline sulfonamide ( …
The actions are blocked by a specific protein kinase A (PKA) inhibitor N-[2-(p-bromocinnamylamino) ethyl]-5-isoquinoline-sulfonamide …
Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.
Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M. Ogino H, et al. Among authors: kohno t. J Neurosci. 2017 Mar 22;37(12):3181-3191. doi: 10.1523/JNEUROSCI.3632-16.2017. Epub 2017 Feb 17. J Neurosci. 2017. PMID: 28213441 Free PMC article.
We previously found that the proteolytic cleavage of Reelin within Reelin repeat 3 (N-t site) abolishes Reelin activity in vitro, but it remains controversial as to whether this effect occurs in vivo Here we partially purified the enzyme that mediates the N-t cleava …
We previously found that the proteolytic cleavage of Reelin within Reelin repeat 3 (N-t site) abolishes Reelin activity in vitro, but …
Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action.
Ohashi N, Kohno T. Ohashi N, et al. Among authors: kohno t. Front Pharmacol. 2020 Nov 30;11:580289. doi: 10.3389/fphar.2020.580289. eCollection 2020. Front Pharmacol. 2020. PMID: 33328986 Free PMC article. Review.
Previously, it was believed that acetaminophen induces analgesia by inhibiting cyclooxygenase enzymes; however, it has been considered recently that the main analgesic mechanism of acetaminophen is its metabolization to N-acylphenolamine (AM404), which then acts on the tra …
Previously, it was believed that acetaminophen induces analgesia by inhibiting cyclooxygenase enzymes; however, it has been considered recen …
LSR antibody promotes apoptosis and disrupts epithelial barriers via signal pathways in endometrial cancer.
Saito K, Konno T, Kohno T, Shimada H, Matsuura M, Okada T, Kura A, Ishii D, Kondoh M, Saito T, Kojima T. Saito K, et al. Among authors: kohno t. Tissue Barriers. 2023 Jul 3;11(3):2106113. doi: 10.1080/21688370.2022.2106113. Epub 2022 Jul 26. Tissue Barriers. 2023. PMID: 35883247 Free PMC article.
We prepared an antibody against the extracellular N-terminal domain of human LSR (LSR-N-ab) and angubindin-1. EEC cell-line Sawano cells in 2D and 2.5D cultures were treated with 100 mug/ml LSR-N-ab or 2.5 mug/ml angubindin-1 with or without protein tyrosine …
We prepared an antibody against the extracellular N-terminal domain of human LSR (LSR-N-ab) and angubindin-1. EEC cell-line Sa …
Evaluating Clinical Genome Sequence Analysis by Watson for Genomics.
Itahashi K, Kondo S, Kubo T, Fujiwara Y, Kato M, Ichikawa H, Koyama T, Tokumasu R, Xu J, Huettner CS, Michelini VV, Parida L, Kohno T, Yamamoto N. Itahashi K, et al. Among authors: kohno t. Front Med (Lausanne). 2018 Nov 9;5:305. doi: 10.3389/fmed.2018.00305. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30474028 Free PMC article.
Results: In 198 patients, in-house genome sequencing detected 785 gene mutations, 40 amplifications, and 22 fusions after eliminating single nucleotide polymorphisms. Breast cancer (n = 40) was the most frequent diagnosis in this analysis, followed by gastric cancer (n …
Results: In 198 patients, in-house genome sequencing detected 785 gene mutations, 40 amplifications, and 22 fusions after eliminating single …
1,290 results