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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 4
1999 2
2000 1
2001 1
2002 4
2003 1
2004 4
2005 2
2006 4
2007 7
2008 8
2009 13
2010 9
2011 7
2012 3
2013 3
2014 2
2017 1
2020 3
2021 1
2022 1
2024 0

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Page 1
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.
Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, Fowler B, Hong SJ, Mohri H, Nair MS, Huang Y, Tay NES, Lee S, Karan C, Resnick SJ, Quinn C, Li W, Shion H, Xia X, Daniels JD, Bartolo-Cruz M, Farina M, Rajbhandari P, Jurtschenko C, Lauber MA, McDonald T, Stokes ME, Hurst BL, Rovis T, Chavez A, Ho DD, Stockwell BR. Liu H, et al. Nat Commun. 2022 Apr 7;13(1):1891. doi: 10.1038/s41467-022-29413-2. Nat Commun. 2022. PMID: 35393402 Free PMC article.
A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells.
Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Frueh F, Hurst BL, Wang H, Kocurek KI, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. Mellott DM, et al. bioRxiv [Preprint]. 2020 Oct 30:2020.10.23.347534. doi: 10.1101/2020.10.23.347534. bioRxiv. 2020. PMID: 33140046 Free PMC article. Updated. Preprint.
mTOR, linking metabolism and immunity.
Xu X, Ye L, Araki K, Ahmed R. Xu X, et al. Semin Immunol. 2012 Dec;24(6):429-35. doi: 10.1016/j.smim.2012.12.005. Epub 2013 Jan 24. Semin Immunol. 2012. PMID: 23352227 Free PMC article. Review.
74 results