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Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species.
Tabebordbar M, Lagerborg KA, Stanton A, King EM, Ye S, Tellez L, Krunnfusz A, Tavakoli S, Widrick JJ, Messemer KA, Troiano EC, Moghadaszadeh B, Peacker BL, Leacock KA, Horwitz N, Beggs AH, Wagers AJ, Sabeti PC. Tabebordbar M, et al. Among authors: horwitz n. Cell. 2021 Sep 16;184(19):4919-4938.e22. doi: 10.1016/j.cell.2021.08.028. Epub 2021 Sep 9. Cell. 2021. PMID: 34506722 Free PMC article.
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells.
Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, Wagers AJ, Michor F, Meissner A, Sadreyev RI, Hochedlinger K. Yagi M, et al. Among authors: horwitz n. Genes Dev. 2021 Sep 1;35(17-18):1209-1228. doi: 10.1101/gad.348678.121. Epub 2021 Aug 19. Genes Dev. 2021. PMID: 34413137 Free PMC article.
Generation of sRAGEhigh transgenic mice to study inflammaging.
Peng Y, Park HS, Tang LA, Horwitz N, Lin L. Peng Y, et al. Among authors: horwitz n. Front Biosci (Landmark Ed). 2019 Jan 1;24(3):555-563. doi: 10.2741/4735. Front Biosci (Landmark Ed). 2019. PMID: 30468673 Free article.