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The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization.
Daniel B, Czimmerer Z, Halasz L, Boto P, Kolostyak Z, Poliska S, Berger WK, Tzerpos P, Nagy G, Horvath A, Hajas G, Cseh T, Nagy A, Sauer S, Francois-Deleuze J, Szatmari I, Bacsi A, Nagy L. Daniel B, et al. Among authors: nagy g, nagy a, nagy l. Genes Dev. 2020 Nov 1;34(21-22):1474-1492. doi: 10.1101/gad.343038.120. Epub 2020 Oct 15. Genes Dev. 2020. PMID: 33060136 Free PMC article.
Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Széles L, Póliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJ, Rühl R, Dezsö B, Nagy L. Széles L, et al. Among authors: nagy g, nagy l. Mol Endocrinol. 2010 Nov;24(11):2218-31. doi: 10.1210/me.2010-0215. Epub 2010 Sep 22. Mol Endocrinol. 2010. PMID: 20861222 Free PMC article.
The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p.
Czimmerer Z, Varga T, Kiss M, Vázquez CO, Doan-Xuan QM, Rückerl D, Tattikota SG, Yan X, Nagy ZS, Daniel B, Poliska S, Horvath A, Nagy G, Varallyay E, Poy MN, Allen JE, Bacso Z, Abreu-Goodger C, Nagy L. Czimmerer Z, et al. Among authors: nagy g, nagy zs, nagy l. Genome Med. 2016 May 31;8(1):63. doi: 10.1186/s13073-016-0315-y. Genome Med. 2016. PMID: 27245778 Free PMC article.
Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration.
Varga T, Mounier R, Patsalos A, Gogolák P, Peloquin M, Horvath A, Pap A, Daniel B, Nagy G, Pintye E, Póliska S, Cuvellier S, Larbi SB, Sansbury BE, Spite M, Brown CW, Chazaud B, Nagy L. Varga T, et al. Among authors: nagy g, nagy l. Immunity. 2016 Nov 15;45(5):1038-1051. doi: 10.1016/j.immuni.2016.10.016. Epub 2016 Nov 8. Immunity. 2016. PMID: 27836432 Free PMC article.
Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages.
Czimmerer Z, Nagy ZS, Nagy G, Horvath A, Silye-Cseh T, Kriston A, Jonas D, Sauer S, Steiner L, Daniel B, Deleuze JF, Nagy L. Czimmerer Z, et al. Among authors: nagy g, nagy zs, nagy l. Mol Cell Endocrinol. 2018 Aug 15;471:63-74. doi: 10.1016/j.mce.2017.07.034. Epub 2017 Jul 31. Mol Cell Endocrinol. 2018. PMID: 28774779
1,427 results