Nakhe AY - Search Results

1

TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced β-cell proliferation.

Altman MK, Schaub CM, Dadi PK, Dickerson MT, Zaborska KE, Nakhe AY, Graff SM, Galletta TJ, Amarnath G, Thorson AS, Gu G, Jacobson DA. Altman MK, et al. Among authors: nakhe ay. Development. 2021 Aug 15;148(16):dev194928. doi: 10.1242/dev.194928. Epub 2021 Aug 16. Development. 2021. PMID: 34345920 Free PMC article.

2

Lactate activation of α-cell K_ATP channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca²⁺ entry.

Zaborska KE, Dadi PK, Dickerson MT, Nakhe AY, Thorson AS, Schaub CM, Graff SM, Stanley JE, Kondapavuluru RS, Denton JS, Jacobson DA. Zaborska KE, et al. Among authors: nakhe ay. Mol Metab. 2020 Dec;42:101056. doi: 10.1016/j.molmet.2020.101056. Epub 2020 Jul 28. Mol Metab. 2020. PMID: 32736089 Free PMC article.

3

Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion.

Dickerson MT, Dadi PK, Butterworth RB, Nakhe AY, Graff SM, Zaborska KE, Schaub CM, Jacobson DA. Dickerson MT, et al. Among authors: nakhe ay. J Physiol. 2020 Nov;598(21):4887-4905. doi: 10.1113/JP279941. Epub 2020 Sep 1. J Physiol. 2020. PMID: 32790176 Free PMC article.

4

A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young.

Graff SM, Johnson SR, Leo PJ, Dadi PK, Dickerson MT, Nakhe AY, McInerney-Leo AM, Marshall M, Zaborska KE, Schaub CM, Brown MA, Jacobson DA, Duncan EL. Graff SM, et al. Among authors: nakhe ay. JCI Insight. 2021 Jul 8;6(13):e138057. doi: 10.1172/jci.insight.138057. JCI Insight. 2021. PMID: 34032641 Free PMC article.

5

Liraglutide increases islet Ca²⁺ oscillation frequency and insulin secretion by activating hyperpolarization-activated cyclic nucleotide-gated channels.

Zaborska KE, Jordan KL, Thorson AS, Dadi PK, Schaub CM, Nakhe AY, Dickerson MT, Lynch JC, Weiss AJ, Dobson JR, Jacobson DA. Zaborska KE, et al. Among authors: nakhe ay. Diabetes Obes Metab. 2022 Sep;24(9):1741-1752. doi: 10.1111/dom.14747. Epub 2022 May 30. Diabetes Obes Metab. 2022. PMID: 35546791 Free PMC article.

6

Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.

Rahim M, Nakhe AY, Banerjee DR, Overway EM, Bosma KJ, Rosch JC, Oeser JK, Wang B, Lippmann ES, Jacobson DA, O'Brien RM, Young JD. Rahim M, et al. Among authors: nakhe ay. J Biol Chem. 2022 Apr;298(4):101729. doi: 10.1016/j.jbc.2022.101729. Epub 2022 Feb 15. J Biol Chem. 2022. PMID: 35176280 Free PMC article.

7

TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet.

Graff SM, Nakhe AY, Dadi PK, Dickerson MT, Dobson JR, Zaborska KE, Ibsen CE, Butterworth RB, Vierra NC, Jacobson DA. Graff SM, et al. Among authors: nakhe ay. Cell Rep. 2024 Jan 23;43(1):113673. doi: 10.1016/j.celrep.2024.113673. Epub 2024 Jan 10. Cell Rep. 2024. PMID: 38206814 Free PMC article.

8

The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.

Nakhe AY, Dadi PK, Kim J, Dickerson MT, Behera S, Dobson JR, Shrestha S, Cartailler JP, Sampson L, Magnuson MA, Jacobson DA. Nakhe AY, et al. bioRxiv [Preprint]. 2024 Feb 27:2023.06.20.545631. doi: 10.1101/2023.06.20.545631. bioRxiv. 2024. PMID: 37546831 Free PMC article. Preprint.

9

IP₃Rs puff along: A SNAPpy dance with IP₃ and Ca².

Nakhe AY, Jacobson DA. Nakhe AY, et al. J Biol Chem. 2023 Mar;299(3):103010. doi: 10.1016/j.jbc.2023.103010. Epub 2023 Feb 10. J Biol Chem. 2023. PMID: 36773801 Free PMC article.

10

G_i/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na⁺/K⁺ ATPase activation.

Dickerson MT, Dadi PK, Zaborska KE, Nakhe AY, Schaub CM, Dobson JR, Wright NM, Lynch JC, Scott CF, Robinson LD, Jacobson DA. Dickerson MT, et al. Among authors: nakhe ay. Nat Commun. 2022 Oct 29;13(1):6461. doi: 10.1038/s41467-022-34166-z. Nat Commun. 2022. PMID: 36309517 Free PMC article.

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