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Characterization of mono- and diaminopyrimidine derivatives as novel, nonpeptide gonadotropin releasing hormone (GnRH) receptor antagonists.
Luthin DR, Hong Y, Tompkins E, Anderes KL, Paderes G, Kraynov EA, Castro MA, Nared-Hood KD, Castillo R, Gregory M, Vazir H, May JM, Anderson MB. Luthin DR, et al. Among authors: nared hood kd. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3635-9. doi: 10.1016/s0960-894x(02)00756-4. Bioorg Med Chem Lett. 2002. PMID: 12443792
Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats.
Anderes KL, Luthin DR, Castillo R, Kraynov EA, Castro M, Nared-Hood K, Gregory ML, Pathak VP, Christie LC, Paderes G, Vazir H, Ye Q, Anderson MB, May JM. Anderes KL, et al. Among authors: nared hood k. J Pharmacol Exp Ther. 2003 May;305(2):688-95. doi: 10.1124/jpet.102.046656. Epub 2003 Jan 24. J Pharmacol Exp Ther. 2003. PMID: 12606616