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Oxidative phosphorylation revisited.
Nath S, Villadsen J. Nath S, et al. Biotechnol Bioeng. 2015 Mar;112(3):429-37. doi: 10.1002/bit.25492. Epub 2015 Jan 2. Biotechnol Bioeng. 2015. PMID: 25384602 Review.
The new findings fit very well with the predictions of Nath's torsional mechanism of energy transduction and ATP synthesis. It is argued that this mechanism, based on at least 15 years of experimental and theoretical work by Sunil Nath, constitutes a fundamen …
The new findings fit very well with the predictions of Nath's torsional mechanism of energy transduction and ATP synthesis. It …
The thermodynamic efficiency of ATP synthesis in oxidative phosphorylation.
Nath S. Nath S. Biophys Chem. 2016 Dec;219:69-74. doi: 10.1016/j.bpc.2016.10.002. Epub 2016 Oct 15. Biophys Chem. 2016. PMID: 27770651
Previous estimates of the thermodynamic efficiency of this vital process have ranged from Lehninger's original back-of-the-envelope calculation of 38% to the often quoted value of 55-60% in current textbooks of biochemistry, to high values of 90% from recent information th …
Previous estimates of the thermodynamic efficiency of this vital process have ranged from Lehninger's original back-of-the-envelope c …
Analysis of molecular mechanisms of ATP synthesis from the standpoint of the principle of electrical neutrality.
Nath S. Nath S. Biophys Chem. 2017 May;224:49-58. doi: 10.1016/j.bpc.2017.03.002. Epub 2017 Mar 8. Biophys Chem. 2017. PMID: 28318906 Review.
It is shown that the obligatory requirement to maintain overall electroneutrality of bulk aqueous phases imposes strong constraints on possible theories of energy coupling and molecular mechanisms of ATP synthesis. Mitchell's chemiosmotic theory is found to violate the ele …
It is shown that the obligatory requirement to maintain overall electroneutrality of bulk aqueous phases imposes strong constraints on possi …
Two-ion theory of energy coupling in ATP synthesis rectifies a fundamental flaw in the governing equations of the chemiosmotic theory.
Nath S. Nath S. Biophys Chem. 2017 Nov;230:45-52. doi: 10.1016/j.bpc.2017.08.005. Epub 2017 Aug 19. Biophys Chem. 2017. PMID: 28882384
Although the theory was strongly criticized by many prominent scientists, the controversy has never been resolved. Here, the mathematical steps of Mitchell's original derivation leading to the principal equation of the chemiosmotic theory are scrutinized, and a fundamental …
Although the theory was strongly criticized by many prominent scientists, the controversy has never been resolved. Here, the mathematical st …
1,284 results