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Year Number of Results
2014 1
2016 3
2017 1
2018 1
2020 1
2021 4
2023 4
2024 1

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15 results

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Page 1
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
He C, Xu K, Zhu X, Dunphy PS, Gudenas B, Lin W, Twarog N, Hover LD, Kwon CH, Kasper LH, Zhang J, Li X, Dalton J, Jonchere B, Mercer KS, Currier DG, Caufield W, Wang Y, Xie J, Broniscer A, Wetmore C, Upadhyaya SA, Qaddoumi I, Klimo P, Boop F, Gajjar A, Zhang J, Orr BA, Robinson GW, Monje M, Freeman Iii BB, Roussel MF, Northcott PA, Chen T, Rankovic Z, Wu G, Chiang J, Tinkle CL, Shelat AA, Baker SJ. He C, et al. Among authors: twarog n. Nat Commun. 2021 Jul 2;12(1):4089. doi: 10.1038/s41467-021-24168-8. Nat Commun. 2021. PMID: 34215733 Free PMC article.
Using response surface models to analyze drug combinations.
Twarog NR, Martinez NE, Gartrell J, Xie J, Tinkle CL, Shelat AA. Twarog NR, et al. Drug Discov Today. 2021 Aug;26(8):2014-2024. doi: 10.1016/j.drudis.2021.06.002. Epub 2021 Jun 10. Drug Discov Today. 2021. PMID: 34119666 Free PMC article. Review.
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Kamens JL, Nance S, Koss C, Xu B, Cotton A, Lam JW, Garfinkle EAR, Nallagatla P, Smith AMR, Mitchell S, Ma J, Currier D, Wright WC, Kavdia K, Pagala VR, Kim W, Wallace LM, Cho JH, Fan Y, Seth A, Twarog N, Choi JK, Obeng EA, Hatley ME, Metzger ML, Inaba H, Jeha S, Rubnitz JE, Peng J, Chen T, Shelat AA, Guy RK, Gruber TA. Kamens JL, et al. Among authors: twarog n. Nat Commun. 2023 Feb 13;14(1):809. doi: 10.1038/s41467-023-36370-x. Nat Commun. 2023. PMID: 36781850 Free PMC article.
ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.
Xie J, Kuriakose T, Bianski B, Twarog N, Savage E, Xu K, Zhu X, He C, Hansen B, Wang H, High A, Li Y, Rehg JE, Tillman HS, Freeman BB, Rankovic Z, Onar-Thomas A, Fan Y, Wu G, Peng J, Miller S, Baker SJ, Shelat AA, Tinkle CL. Xie J, et al. Among authors: twarog n. Neuro Oncol. 2023 Oct 3;25(10):1828-1841. doi: 10.1093/neuonc/noad064. Neuro Oncol. 2023. PMID: 36971093 Free PMC article.
Orthotopic patient-derived xenografts of paediatric solid tumours.
Stewart E, Federico SM, Chen X, Shelat AA, Bradley C, Gordon B, Karlstrom A, Twarog NR, Clay MR, Bahrami A, Freeman BB 3rd, Xu B, Zhou X, Wu J, Honnell V, Ocarz M, Blankenship K, Dapper J, Mardis ER, Wilson RK, Downing J, Zhang J, Easton J, Pappo A, Dyer MA. Stewart E, et al. Among authors: twarog nr. Nature. 2017 Sep 7;549(7670):96-100. doi: 10.1038/nature23647. Epub 2017 Aug 30. Nature. 2017. PMID: 28854174 Free PMC article.
Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
Kamens JL, Nance S, Koss C, Xu B, Cotton A, Lam JW, Garfinkle EAR, Nallagatla P, Smith AMR, Mitchell S, Ma J, Currier D, Wright WC, Kavdia K, Pagala VR, Kim W, Wallace LM, Cho JH, Fan Y, Seth A, Twarog N, Choi JK, Obeng EA, Hatley ME, Metzger ML, Inaba H, Jeha S, Rubnitz JE, Peng J, Chen T, Shelat AA, Guy RK, Gruber TA. Kamens JL, et al. Among authors: twarog n. Nat Commun. 2023 Mar 9;14(1):1297. doi: 10.1038/s41467-023-37141-4. Nat Commun. 2023. PMID: 36894563 Free PMC article. No abstract available.
Targeting the DNA repair pathway in Ewing sarcoma.
Stewart E, Goshorn R, Bradley C, Griffiths LM, Benavente C, Twarog NR, Miller GM, Caufield W, Freeman BB 3rd, Bahrami A, Pappo A, Wu J, Loh A, Karlström Å, Calabrese C, Gordon B, Tsurkan L, Hatfield MJ, Potter PM, Snyder SE, Thiagarajan S, Shirinifard A, Sablauer A, Shelat AA, Dyer MA. Stewart E, et al. Among authors: twarog nr. Cell Rep. 2014 Nov 6;9(3):829-41. doi: 10.1016/j.celrep.2014.09.028. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437539 Free PMC article.
SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents.
Gartrell J, Mellado-Largarde M, Clay MR, Bahrami A, Sahr NA, Sykes A, Blankenship K, Hoffmann L, Xie J, Cho HP, Twarog N, Connelly M, Yan KK, Yu J, Porter SN, Pruett-Miller SM, Neale G, Tinkle CL, Federico SM, Stewart EA, Shelat AA. Gartrell J, et al. Among authors: twarog n. Mol Cancer Ther. 2021 Nov;20(11):2151-2165. doi: 10.1158/1535-7163.MCT-21-0089. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413129 Free PMC article.
15 results