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Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. Corley MJ, et al. Among authors: ndhlovu lc. J Leukoc Biol. 2021 Jul;110(1):21-26. doi: 10.1002/JLB.5HI0720-466R. Epub 2021 Jan 19. J Leukoc Biol. 2021. PMID: 33464637 Free PMC article.
Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection.
SenGupta D, Tandon R, Vieira RG, Ndhlovu LC, Lown-Hecht R, Ormsby CE, Loh L, Jones RB, Garrison KE, Martin JN, York VA, Spotts G, Reyes-Terán G, Ostrowski MA, Hecht FM, Deeks SG, Nixon DF. SenGupta D, et al. Among authors: ndhlovu lc. J Virol. 2011 Jul;85(14):6977-85. doi: 10.1128/JVI.00179-11. Epub 2011 Apr 27. J Virol. 2011. PMID: 21525339 Free PMC article.
Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.
Tandon R, Chew GM, Byron MM, Borrow P, Niki T, Hirashima M, Barbour JD, Norris PJ, Lanteri MC, Martin JN, Deeks SG, Ndhlovu LC. Tandon R, et al. Among authors: ndhlovu lc. AIDS Res Hum Retroviruses. 2014 Jul;30(7):654-64. doi: 10.1089/AID.2014.0004. Epub 2014 May 28. AIDS Res Hum Retroviruses. 2014. PMID: 24786365 Free PMC article.
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques.
Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, Ishii N, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC. Fujita T, et al. Among authors: ndhlovu lc. J Immunol. 2014 Dec 1;193(11):5576-83. doi: 10.4049/jimmunol.1400961. Epub 2014 Oct 27. J Immunol. 2014. PMID: 25348621 Free PMC article.
Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.
Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA. Clayton KL, et al. Among authors: ndhlovu lc. J Virol. 2015 Apr;89(7):3723-36. doi: 10.1128/JVI.00006-15. Epub 2015 Jan 21. J Virol. 2015. PMID: 25609823 Free PMC article.
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. Chew GM, et al. Among authors: ndhlovu lc. PLoS Pathog. 2016 Jan 7;12(1):e1005349. doi: 10.1371/journal.ppat.1005349. eCollection 2016 Jan. PLoS Pathog. 2016. PMID: 26741490 Free PMC article.
Strategies to target non-T-cell HIV reservoirs.
Sacha JB, Ndhlovu LC. Sacha JB, et al. Among authors: ndhlovu lc. Curr Opin HIV AIDS. 2016 Jul;11(4):376-82. doi: 10.1097/COH.0000000000000283. Curr Opin HIV AIDS. 2016. PMID: 27023285 Free PMC article. Review.
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK. Abdel-Mohsen M, et al. Among authors: ndhlovu lc. PLoS Pathog. 2016 Jun 2;12(6):e1005677. doi: 10.1371/journal.ppat.1005677. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27253379 Free PMC article.
181 results