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In a Rat Model of Opioid Maintenance, the G Protein-Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia.
Bossert JM, Kiyatkin EA, Korah H, Hoots JK, Afzal A, Perekopskiy D, Thomas S, Fredriksson I, Blough BE, Negus SS, Epstein DH, Shaham Y. Bossert JM, et al. Among authors: negus ss. Biol Psychiatry. 2020 Dec 15;88(12):935-944. doi: 10.1016/j.biopsych.2020.02.014. Epub 2020 Feb 24. Biol Psychiatry. 2020. PMID: 32305216 Free PMC article.
Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys.
Negus SS, Mello NK, Blough BE, Baumann MH, Rothman RB. Negus SS, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):627-36. doi: 10.1124/jpet.106.107383. Epub 2006 Oct 27. J Pharmacol Exp Ther. 2007. PMID: 17071819
294 results