Nelson EA - Search Results

1

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

Nelson EA, Walker SR, Kepich A, Gashin LB, Hideshima T, Ikeda H, Chauhan D, Anderson KC, Frank DA. Nelson EA, et al. Blood. 2008 Dec 15;112(13):5095-102. doi: 10.1182/blood-2007-12-129718. Epub 2008 Sep 29. Blood. 2008. PMID: 18824601 Free PMC article.

2

Reciprocal effects of STAT5 and STAT3 in breast cancer.

Walker SR, Nelson EA, Zou L, Chaudhury M, Signoretti S, Richardson A, Frank DA. Walker SR, et al. Among authors: nelson ea. Mol Cancer Res. 2009 Jun;7(6):966-76. doi: 10.1158/1541-7786.MCR-08-0238. Epub 2009 Jun 2. Mol Cancer Res. 2009. PMID: 19491198

3

Microtubule-targeted chemotherapeutic agents inhibit signal transducer and activator of transcription 3 (STAT3) signaling.

Walker SR, Chaudhury M, Nelson EA, Frank DA. Walker SR, et al. Among authors: nelson ea. Mol Pharmacol. 2010 Nov;78(5):903-8. doi: 10.1124/mol.110.066316. Epub 2010 Aug 6. Mol Pharmacol. 2010. PMID: 20693278

4

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors.

Nelson EA, Walker SR, Weisberg E, Bar-Natan M, Barrett R, Gashin LB, Terrell S, Klitgaard JL, Santo L, Addorio MR, Ebert BL, Griffin JD, Frank DA. Nelson EA, et al. Blood. 2011 Mar 24;117(12):3421-9. doi: 10.1182/blood-2009-11-255232. Epub 2011 Jan 13. Blood. 2011. PMID: 21233313 Free PMC article.

5

STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas.

Walker SR, Nelson EA, Frank DA. Walker SR, et al. Among authors: nelson ea. Oncogene. 2007 Jan 11;26(2):224-33. doi: 10.1038/sj.onc.1209775. Epub 2006 Jul 3. Oncogene. 2007. PMID: 16819511

6

Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification.

Nelson EA, Walker SR, Alvarez JV, Frank DA. Nelson EA, et al. J Biol Chem. 2004 Dec 24;279(52):54724-30. doi: 10.1074/jbc.M408464200. Epub 2004 Oct 20. J Biol Chem. 2004. PMID: 15498775 Free article.

7

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo.

Zorn E, Nelson EA, Mohseni M, Porcheray F, Kim H, Litsa D, Bellucci R, Raderschall E, Canning C, Soiffer RJ, Frank DA, Ritz J. Zorn E, et al. Among authors: nelson ea. Blood. 2006 Sep 1;108(5):1571-9. doi: 10.1182/blood-2006-02-004747. Epub 2006 Apr 27. Blood. 2006. PMID: 16645171 Free PMC article.

8

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.

Nelson EA, Walker SR, Li W, Liu XS, Frank DA. Nelson EA, et al. J Biol Chem. 2006 Sep 8;281(36):26216-24. doi: 10.1074/jbc.M605001200. Epub 2006 Jul 13. J Biol Chem. 2006. PMID: 16840779 Free PMC article.

9

Antimyeloma activity of a multitargeted kinase inhibitor, AT9283, via potent Aurora kinase and STAT3 inhibition either alone or in combination with lenalidomide.

Santo L, Hideshima T, Cirstea D, Bandi M, Nelson EA, Gorgun G, Rodig S, Vallet S, Pozzi S, Patel K, Unitt C, Squires M, Hu Y, Chauhan D, Mahindra A, Munshi NC, Anderson KC, Raje N. Santo L, et al. Among authors: nelson ea. Clin Cancer Res. 2011 May 15;17(10):3259-71. doi: 10.1158/1078-0432.CCR-10-3012. Epub 2011 Mar 23. Clin Cancer Res. 2011. PMID: 21430070 Free PMC article.

10

A chemical biology approach to developing STAT inhibitors: molecular strategies for accelerating clinical translation.

Nelson EA, Sharma SV, Settleman J, Frank DA. Nelson EA, et al. Oncotarget. 2011 Jun;2(6):518-24. doi: 10.18632/oncotarget.296. Oncotarget. 2011. PMID: 21680956 Free PMC article. Review.

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