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One-year entecavir or lamivudine therapy results in reduction of hepatitis B virus intrahepatic covalently closed circular DNA levels.
Antivir Ther. 2006;11(7):909-16.
Antivir Ther. 2006.
PMID: 17302253
Clinical Trial.
A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B.
Yuen MF, Kim J, Kim CR, Ngai V, Yuen JC, Min C, Kang HM, Shin BS, Yoo SD, Lai CL.
Yuen MF, et al.
Antivir Ther. 2006;11(8):977-83.
Antivir Ther. 2006.
PMID: 17302367
Clinical Trial.
Item in Clipboard
Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B.
Lai CL, Wong D, Ip P, Kopaniszen M, Seto WK, Fung J, Huang FY, Lee B, Cullaro G, Chong CK, Wu R, Cheng C, Yuen J, Ngai V, Yuen MF.
Lai CL, et al.
J Hepatol. 2017 Feb;66(2):275-281. doi: 10.1016/j.jhep.2016.08.022. Epub 2016 Sep 14.
J Hepatol. 2017.
PMID: 27639844
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Long-term lamivudine therapy reduces the risk of long-term complications of chronic hepatitis B infection even in patients without advanced disease.
Yuen MF, Seto WK, Chow DH, Tsui K, Wong DK, Ngai VW, Wong BC, Fung J, Yuen JC, Lai CL.
Yuen MF, et al. Among authors: ngai vw.
Antivir Ther. 2007;12(8):1295-303.
Antivir Ther. 2007.
PMID: 18240869
Clinical Trial.
Item in Clipboard
Pharmacokinetics of LB80331 and LB80317 following oral administration of LB80380, a new antiviral agent for chronic hepatitis B (CHB), in healthy adult subjects, CHB patients, and mice.
Yuen MF, Lee SH, Kang HM, Kim CR, Kim J, Ngai V, Lai CL.
Yuen MF, et al.
Antimicrob Agents Chemother. 2009 May;53(5):1779-85. doi: 10.1128/AAC.01290-08. Epub 2009 Feb 17.
Antimicrob Agents Chemother. 2009.
PMID: 19223649
Free PMC article.
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