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Active DNA demethylation promotes cell fate specification and the DNA damage response.
Wang D, Wu W, Callen E, Pavani R, Zolnerowich N, Kodali S, Zong D, Wong N, Noriega S, Nathan WJ, Matos-Rodrigues G, Chari R, Kruhlak MJ, Livak F, Ward M, Caldecott K, Di Stefano B, Nussenzweig A. Wang D, et al. Among authors: zolnerowich n. Science. 2022 Dec 2;378(6623):983-989. doi: 10.1126/science.add9838. Epub 2022 Dec 1. Science. 2022. PMID: 36454826 Free PMC article.
DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells.
Fowler FC, Chen BR, Zolnerowich N, Wu W, Pavani R, Paiano J, Peart C, Chen Z, Nussenzweig A, Sleckman BP, Tyler JK. Fowler FC, et al. Among authors: zolnerowich n. Elife. 2022 May 16;11:e74700. doi: 10.7554/eLife.74700. Elife. 2022. PMID: 35575473 Free PMC article.
Role of 53BP1 in end protection and DNA synthesis at DNA breaks.
Paiano J, Zolnerowich N, Wu W, Pavani R, Wang C, Li H, Zheng L, Shen B, Sleckman BP, Chen BR, Nussenzweig A. Paiano J, et al. Among authors: zolnerowich n. Genes Dev. 2021 Oct 1;35(19-20):1356-1367. doi: 10.1101/gad.348667.121. Epub 2021 Sep 9. Genes Dev. 2021. PMID: 34503990 Free PMC article.
CTCF is a barrier for 2C-like reprogramming.
Olbrich T, Vega-Sendino M, Tillo D, Wu W, Zolnerowich N, Pavani R, Tran AD, Domingo CN, Franco M, Markiewicz-Potoczny M, Pegoraro G, FitzGerald PC, Kruhlak MJ, Lazzerini-Denchi E, Nora EP, Nussenzweig A, Ruiz S. Olbrich T, et al. Among authors: zolnerowich n. Nat Commun. 2021 Aug 11;12(1):4856. doi: 10.1038/s41467-021-25072-x. Nat Commun. 2021. PMID: 34381034 Free PMC article.