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"Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic.
Gordish-Dressman H, Willmann R, Dalle Pazze L, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbreun AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Patrick Gonzalez J, Grounds MD, Nichols A, Partridge T, Passini M, Sanarica F, Schnell FJ, Wells DJ, Yokota T, Young CS, Zhong Z, Spurney C, Spencer M, De Luca A, Nagaraju K, Aartsma-Rus A. Gordish-Dressman H, et al. Among authors: nichols a. J Neuromuscul Dis. 2018;5(4):407-417. doi: 10.3233/JND-180324. J Neuromuscul Dis. 2018. PMID: 30198876 Free PMC article.
Disease-modifying effects of edasalonexent, an NF-κB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial.
Finkel RS, Finanger E, Vandenborne K, Sweeney HL, Tennekoon G, Shieh PB, Willcocks R, Walter G, Rooney WD, Forbes SC, Triplett WT, Yum SW, Mancini M, MacDougall J, Fretzen A, Bista P, Nichols A, Donovan JM. Finkel RS, et al. Among authors: nichols a. Neuromuscul Disord. 2021 May;31(5):385-396. doi: 10.1016/j.nmd.2021.02.001. Epub 2021 Feb 4. Neuromuscul Disord. 2021. PMID: 33678513 Free article. Clinical Trial.
Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid.
Vu CB, Bemis JE, Benson E, Bista P, Carney D, Fahrner R, Lee D, Liu F, Lonkar P, Milne JC, Nichols AJ, Picarella D, Shoelson A, Smith J, Ting A, Wensley A, Yeager M, Zimmer M, Jirousek MR. Vu CB, et al. Among authors: nichols aj. J Med Chem. 2016 Feb 11;59(3):1217-31. doi: 10.1021/acs.jmedchem.5b01961. Epub 2016 Feb 1. J Med Chem. 2016. PMID: 26784936
CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice.
Zimmer M, Bista P, Benson EL, Lee DY, Liu F, Picarella D, Vega RB, Vu CB, Yeager M, Ding M, Liang G, Horton JD, Kleemann R, Kooistra T, Morrison MC, Wielinga PY, Milne JC, Jirousek MR, Nichols AJ. Zimmer M, et al. Hepatol Commun. 2017 May 12;1(4):311-325. doi: 10.1002/hep4.1042. eCollection 2017 Jun. Hepatol Commun. 2017. PMID: 29404461 Free PMC article.
Metabolism of bioconjugate therapeutics: why, when, and how?
Liu H, Bolleddula J, Nichols A, Tang L, Zhao Z, Prakash C. Liu H, et al. Among authors: nichols a. Drug Metab Rev. 2020 Feb;52(1):66-124. doi: 10.1080/03602532.2020.1716784. Epub 2020 Feb 11. Drug Metab Rev. 2020. PMID: 32045530 Review.
Fatty Acid Cysteamine Conjugates as Novel and Potent Autophagy Activators That Enhance the Correction of Misfolded F508del-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
Vu CB, Bridges RJ, Pena-Rasgado C, Lacerda AE, Bordwell C, Sewell A, Nichols AJ, Chandran S, Lonkar P, Picarella D, Ting A, Wensley A, Yeager M, Liu F. Vu CB, et al. Among authors: nichols aj. J Med Chem. 2017 Jan 12;60(1):458-473. doi: 10.1021/acs.jmedchem.6b01539. Epub 2016 Dec 23. J Med Chem. 2017. PMID: 27976892
1,053 results