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Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Custers L, Khabirova E, Coorens THH, Oliver TRW, Calandrini C, Young MD, Vieira Braga FA, Ellis P, Mamanova L, Segers H, Maat A, Kool M, Hoving EW, van den Heuvel-Eibrink MM, Nicholson J, Straathof K, Hook L, de Krijger RR, Trayers C, Allinson K, Behjati S, Drost J. Custers L, et al. Among authors: nicholson j. Nat Commun. 2021 Mar 3;12(1):1407. doi: 10.1038/s41467-021-21675-6. Nat Commun. 2021. PMID: 33658498 Free PMC article.
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Young MD, et al. Among authors: nicholson j. Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699. Science. 2018. PMID: 30093597 Free PMC article.
Spatiotemporal immune zonation of the human kidney.
Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR. Stewart BJ, et al. Among authors: nicholson j. Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031. Science. 2019. PMID: 31604275 Free PMC article.
Embryonal precursors of Wilms tumor.
Coorens THH, Treger TD, Al-Saadi R, Moore L, Tran MGB, Mitchell TJ, Tugnait S, Thevanesan C, Young MD, Oliver TRW, Oostveen M, Collord G, Tarpey PS, Cagan A, Hooks Y, Brougham M, Reynolds BC, Barone G, Anderson J, Jorgensen M, Burke GAA, Visser J, Nicholson JC, Smeulders N, Mushtaq I, Stewart GD, Campbell PJ, Wedge DC, Martincorena I, Rampling D, Hook L, Warren AY, Coleman N, Chowdhury T, Sebire N, Drost J, Saeb-Parsy K, Stratton MR, Straathof K, Pritchard-Jones K, Behjati S. Coorens THH, et al. Among authors: nicholson jc. Science. 2019 Dec 6;366(6470):1247-1251. doi: 10.1126/science.aax1323. Science. 2019. PMID: 31806814 Free PMC article.
The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer.
Trotman J, Armstrong R, Firth H, Trayers C, Watkins J, Allinson K, Jacques TS, Nicholson JC, Burke GAA; Genomics England Research Consortium; Behjati S, Murray MJ, Hook CE, Tarpey P. Trotman J, et al. Among authors: nicholson jc. Br J Cancer. 2022 Jul;127(1):137-144. doi: 10.1038/s41416-022-01788-5. Epub 2022 Apr 22. Br J Cancer. 2022. PMID: 35449451 Free PMC article.
Small non-coding RNA sequencing reveals global dysregulation of piwi-interacting RNA (piRNA) expression in gonadal malignant germ cell tumours.
Laidlaw S, Alonso-Crisostomo L, Bailey S, Saini HK, Molnár A, Nicholson JC, Enright AJ, Scarpini CG, Rahbari R, Coleman N, Murray MJ; on behalf the Children's Cancer and Leukaemia Group. Laidlaw S, et al. Among authors: nicholson jc. Andrology. 2023 May;11(4):738-755. doi: 10.1111/andr.13312. Epub 2022 Oct 26. Andrology. 2023. PMID: 36254403
Targeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption.
Bailey S, Ferraresso M, Alonso-Crisostomo L, Ward D, Smith S, Nicholson JC, Saini H, Enright AJ, Scarpini CG, Coleman N, Murray MJ. Bailey S, et al. Among authors: nicholson jc. Br J Cancer. 2023 Oct;129(9):1451-1461. doi: 10.1038/s41416-023-02453-1. Epub 2023 Oct 3. Br J Cancer. 2023. PMID: 37789102 Free PMC article.
2,248 results