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Rare HLA drive additional HIV evolution compared to more frequent alleles.
Rousseau CM, Lockhart DW, Listgarten J, Maley SN, Kadie C, Learn GH, Nickle DC, Heckerman DE, Deng W, Brander C, Ndung'u T, Coovadia H, Goulder PJ, Korber BT, Walker BD, Mullins JI. Rousseau CM, et al. Among authors: nickle dc. AIDS Res Hum Retroviruses. 2009 Mar;25(3):297-303. doi: 10.1089/aid.2008.0208. AIDS Res Hum Retroviruses. 2009. PMID: 19327049 Free PMC article.
Coping with viral diversity in HIV vaccine design.
Nickle DC, Rolland M, Jensen MA, Pond SL, Deng W, Seligman M, Heckerman D, Mullins JI, Jojic N. Nickle DC, et al. PLoS Comput Biol. 2007 Apr 27;3(4):e75. doi: 10.1371/journal.pcbi.0030075. PLoS Comput Biol. 2007. PMID: 17465674 Free PMC article.
HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.
Rousseau CM, Daniels MG, Carlson JM, Kadie C, Crawford H, Prendergast A, Matthews P, Payne R, Rolland M, Raugi DN, Maust BS, Learn GH, Nickle DC, Coovadia H, Ndung'u T, Frahm N, Brander C, Walker BD, Goulder PJ, Bhattacharya T, Heckerman DE, Korber BT, Mullins JI. Rousseau CM, et al. Among authors: nickle dc. J Virol. 2008 Jul;82(13):6434-46. doi: 10.1128/JVI.02455-07. Epub 2008 Apr 23. J Virol. 2008. PMID: 18434400 Free PMC article.
Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure.
Ngumbela KC, Day CL, Mncube Z, Nair K, Ramduth D, Thobakgale C, Moodley E, Reddy S, de Pierres C, Mkhwanazi N, Bishop K, van der Stok M, Ismail N, Honeyborne I, Crawford H, Kavanagh DG, Rousseau C, Nickle D, Mullins J, Heckerman D, Korber B, Coovadia H, Kiepiela P, Goulder PJ, Walker BD. Ngumbela KC, et al. AIDS Res Hum Retroviruses. 2008 Jan;24(1):72-82. doi: 10.1089/aid.2007.0124. AIDS Res Hum Retroviruses. 2008. PMID: 18275350
Immunogen sequence: the fourth tier of AIDS vaccine design.
Mullins JI, Nickle DC, Heath L, Rodrigo AG, Learn GH. Mullins JI, et al. Among authors: nickle dc. Expert Rev Vaccines. 2004 Aug;3(4 Suppl):S151-9. doi: 10.1586/14760584.3.4.s151. Expert Rev Vaccines. 2004. PMID: 15285713 Review.
Pervasive genomic recombination of HIV-1 in vivo.
Shriner D, Rodrigo AG, Nickle DC, Mullins JI. Shriner D, et al. Among authors: nickle dc. Genetics. 2004 Aug;167(4):1573-83. doi: 10.1534/genetics.103.023382. Genetics. 2004. PMID: 15342499 Free PMC article.
126 results