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Page 1
Signaling mechanisms inducing hyporesponsiveness of phagocytes during systemic inflammation.
Blood. 2019 Jul 11;134(2):134-146. doi: 10.1182/blood.2019000320. Epub 2019 May 10.
Blood. 2019.
PMID: 31076441
Free article.
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H.
Klotz L, et al. Among authors: freise n.
Sci Transl Med. 2019 May 1;11(490):eaao5563. doi: 10.1126/scitranslmed.aao5563.
Sci Transl Med. 2019.
PMID: 31043571
Clinical Trial.
Item in Clipboard
Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity.
Hucke S, Eschborn M, Liebmann M, Herold M, Freise N, Engbers A, Ehling P, Meuth SG, Roth J, Kuhlmann T, Wiendl H, Klotz L.
Hucke S, et al. Among authors: freise n.
J Autoimmun. 2016 Feb;67:90-101. doi: 10.1016/j.jaut.2015.11.001. Epub 2015 Nov 14.
J Autoimmun. 2016.
PMID: 26584738
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The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion.
Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck AK, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth SG, Zipp F, Hemmer B, Engel DR, Roth J, Kuhlmann T, Wiendl H, Klotz L.
Hucke S, et al. Among authors: freise n.
Acta Neuropathol. 2016 Sep;132(3):413-31. doi: 10.1007/s00401-016-1593-6. Epub 2016 Jul 6.
Acta Neuropathol. 2016.
PMID: 27383204
Item in Clipboard
Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8.
Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T.
Fassl SK, et al. Among authors: freise n.
J Immunol. 2015 Jan 15;194(2):575-83. doi: 10.4049/jimmunol.1401085. Epub 2014 Dec 10.
J Immunol. 2015.
PMID: 25505274
Clinical Trial.
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