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Page 1
Basement membrane stiffness determines metastases formation.
Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Reuten R, et al. Among authors: nikodemus d. Nat Mater. 2021 Jun;20(6):892-903. doi: 10.1038/s41563-020-00894-0. Epub 2021 Jan 25. Nat Mater. 2021. PMID: 33495631
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J. Meier M, et al. Among authors: nikodemus d. Nat Commun. 2023 Mar 3;14(1):1226. doi: 10.1038/s41467-023-36692-w. Nat Commun. 2023. PMID: 36869049 Free PMC article.
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
Kruse T, Gnosa SP, Nasa I, Garvanska DH, Hein JB, Nguyen H, Samsøe-Petersen J, Lopez-Mendez B, Hertz EPT, Schwarz J, Pena HS, Nikodemus D, Kveiborg M, Kettenbach AN, Nilsson J. Kruse T, et al. Among authors: nikodemus d. EMBO J. 2020 Jul 1;39(13):e103695. doi: 10.15252/embj.2019103695. Epub 2020 May 13. EMBO J. 2020. PMID: 32400009 Free PMC article.
Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
Grandin M, Meier M, Delcros JG, Nikodemus D, Reuten R, Patel TR, Goldschneider D, Orriss G, Krahn N, Boussouar A, Abes R, Dean Y, Neves D, Bernet A, Depil S, Schneiders F, Poole K, Dante R, Koch M, Mehlen P, Stetefeld J. Grandin M, et al. Among authors: nikodemus d. Cancer Cell. 2016 Feb 8;29(2):173-85. doi: 10.1016/j.ccell.2016.01.001. Cancer Cell. 2016. PMID: 26859457 Free article.
Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P, Stetefeld J, Koch M. Reuten R, et al. Among authors: nikodemus d. Nat Commun. 2016 Nov 30;7:13515. doi: 10.1038/ncomms13515. Nat Commun. 2016. PMID: 27901020 Free PMC article.