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Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.
Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T. Negishi H, et al. Among authors: nishio j. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19884-9. doi: 10.1073/pnas.1320145110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248350 Free PMC article.
PGE2 induced in and released by dying cells functions as an inhibitory DAMP.
Hangai S, Ao T, Kimura Y, Matsuki K, Kawamura T, Negishi H, Nishio J, Kodama T, Taniguchi T, Yanai H. Hangai S, et al. Among authors: nishio j. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3844-9. doi: 10.1073/pnas.1602023113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001836 Free PMC article.
Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice.
Yanai H, Chiba S, Hangai S, Kometani K, Inoue A, Kimura Y, Abe T, Kiyonari H, Nishio J, Taguchi-Atarashi N, Mizushima Y, Negishi H, Grosschedl R, Taniguchi T. Yanai H, et al. Among authors: nishio j. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5253-5258. doi: 10.1073/pnas.1803936115. Epub 2018 Apr 30. Proc Natl Acad Sci U S A. 2018. PMID: 29712834 Free PMC article.
286 results