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Page 1
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D. Achreja A, et al. Among authors: meurs n. Nat Metab. 2022 Sep;4(9):1119-1137. doi: 10.1038/s42255-022-00636-3. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131208
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.
Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE. Zhao S, et al. Among authors: meurs n. Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069. Cell Rep. 2016. PMID: 27760311 Free PMC article.
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues.
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. Wallace M, et al. Among authors: meurs n. Nat Chem Biol. 2018 Nov;14(11):1021-1031. doi: 10.1038/s41589-018-0132-2. Epub 2018 Oct 16. Nat Chem Biol. 2018. PMID: 30327559 Free PMC article.
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours.
Zhu Z, Achreja A, Meurs N, Animasahun O, Owen S, Mittal A, Parikh P, Lo TW, Franco-Barraza J, Shi J, Gunchick V, Sherman MH, Cukierman E, Pickering AM, Maitra A, Sahai V, Morgan MA, Nagrath S, Lawrence TS, Nagrath D. Zhu Z, et al. Among authors: meurs n. Nat Metab. 2020 Aug;2(8):775-792. doi: 10.1038/s42255-020-0226-5. Epub 2020 Jul 6. Nat Metab. 2020. PMID: 32694827 Free PMC article.
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A. Collin de l'Hortet A, et al. Among authors: meurs n. Cell Metab. 2019 Aug 6;30(2):385-401.e9. doi: 10.1016/j.cmet.2019.06.017. Cell Metab. 2019. PMID: 31390551 Free PMC article.
Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children.
Sawh MC, Wallace M, Shapiro E, Goyal NP, Newton KP, Yu EL, Bross C, Durelle J, Knott C, Gangoiti JA, Barshop BA, Gengatharan JM, Meurs N, Schlein A, Middleton MS, Sirlin CB, Metallo CM, Schwimmer JB. Sawh MC, et al. Among authors: meurs n. J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):e90-e96. doi: 10.1097/MPG.0000000000003040. J Pediatr Gastroenterol Nutr. 2021. PMID: 33399331 Free PMC article.
Long chain monomethyl branched-chain fatty acid levels in human milk vary with gestational weight gain.
O'Sullivan A, Brady E, Lafferty L, O'Shea F, O'Regan Z, Meurs N, Baldini M, Gengatharan J, Metallo CM, Wallace M. O'Sullivan A, et al. Among authors: meurs n. Prostaglandins Leukot Essent Fatty Acids. 2024 Jan 22;201:102607. doi: 10.1016/j.plefa.2024.102607. Online ahead of print. Prostaglandins Leukot Essent Fatty Acids. 2024. PMID: 38277883 Free article.