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Page 1
The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.
Fukuda T, Furukawa K, Maruyama T, Yamashita SI, Noshiro D, Song C, Ogasawara Y, Okuyama K, Alam JM, Hayatsu M, Saigusa T, Inoue K, Ikeda K, Takai A, Chen L, Lahiri V, Okada Y, Shibata S, Murata K, Klionsky DJ, Noda NN, Kanki T. Fukuda T, et al. Among authors: noshiro d. Mol Cell. 2023 Jun 15;83(12):2045-2058.e9. doi: 10.1016/j.molcel.2023.04.022. Epub 2023 May 15. Mol Cell. 2023. PMID: 37192628
Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex.
Kurusu R, Fujimoto Y, Morishita H, Noshiro D, Takada S, Yamano K, Tanaka H, Arai R, Kageyama S, Funakoshi T, Komatsu-Hirota S, Taka H, Kazuno S, Miura Y, Koike M, Wakai T, Waguri S, Noda NN, Komatsu M. Kurusu R, et al. Among authors: noshiro d. Dev Cell. 2023 Jul 10;58(13):1189-1205.e11. doi: 10.1016/j.devcel.2023.04.015. Epub 2023 May 15. Dev Cell. 2023. PMID: 37192622
The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Ishimura R, El-Gowily AH, Noshiro D, Komatsu-Hirota S, Ono Y, Shindo M, Hatta T, Abe M, Uemura T, Lee-Okada HC, Mohamed TM, Yokomizo T, Ueno T, Sakimura K, Natsume T, Sorimachi H, Inada T, Waguri S, Noda NN, Komatsu M. Ishimura R, et al. Among authors: noshiro d. Nat Commun. 2022 Dec 21;13(1):7857. doi: 10.1038/s41467-022-35501-0. Nat Commun. 2022. PMID: 36543799 Free PMC article.
Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Ikeda R, Noshiro D, Morishita H, Takada S, Kageyama S, Fujioka Y, Funakoshi T, Komatsu-Hirota S, Arai R, Ryzhii E, Abe M, Koga T, Motohashi H, Nakao M, Sakimura K, Horii A, Waguri S, Ichimura Y, Noda NN, Komatsu M. Ikeda R, et al. Among authors: noshiro d. EMBO J. 2023 Jul 17;42(14):e113349. doi: 10.15252/embj.2022113349. Epub 2023 Jun 12. EMBO J. 2023. PMID: 37306101 Free PMC article.
Phase separation organizes the site of autophagosome formation.
Fujioka Y, Alam JM, Noshiro D, Mouri K, Ando T, Okada Y, May AI, Knorr RL, Suzuki K, Ohsumi Y, Noda NN. Fujioka Y, et al. Among authors: noshiro d. Nature. 2020 Feb;578(7794):301-305. doi: 10.1038/s41586-020-1977-6. Epub 2020 Feb 5. Nature. 2020. PMID: 32025038
A glutamine sensor that directly activates TORC1.
Tanigawa M, Yamamoto K, Nagatoishi S, Nagata K, Noshiro D, Noda NN, Tsumoto K, Maeda T. Tanigawa M, et al. Among authors: noshiro d. Commun Biol. 2021 Sep 17;4(1):1093. doi: 10.1038/s42003-021-02625-w. Commun Biol. 2021. PMID: 34535752 Free PMC article.
p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M. Kageyama S, et al. Among authors: noshiro d. Nat Commun. 2021 Jan 4;12(1):16. doi: 10.1038/s41467-020-20185-1. Nat Commun. 2021. PMID: 33397898 Free PMC article.
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN. Matoba K, et al. Among authors: noshiro d. Nat Struct Mol Biol. 2020 Dec;27(12):1185-1193. doi: 10.1038/s41594-020-00518-w. Epub 2020 Oct 26. Nat Struct Mol Biol. 2020. PMID: 33106658
24 results