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Page 1
Detection of Lung Tumor Progression in Mice by Ultrasound Imaging.
J Vis Exp. 2020 Feb 27;(156). doi: 10.3791/60565.
J Vis Exp. 2020.
PMID: 32176201
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer.
Ghaddar N, Wang S, Woodvine B, Krishnamoorthy J, van Hoef V, Darini C, Kazimierczak U, Ah-Son N, Popper H, Johnson M, Officer L, Teodósio A, Broggini M, Mann KK, Hatzoglou M, Topisirovic I, Larsson O, Le Quesne J, Koromilas AE.
Ghaddar N, et al.
Nat Commun. 2021 Jul 30;12(1):4651. doi: 10.1038/s41467-021-24661-0.
Nat Commun. 2021.
PMID: 34330898
Free PMC article.
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Access to high-impact mutations constrains the evolution of antibiotic resistance in soft agar.
Ghaddar N, Hashemidahaj M, Findlay BL.
Ghaddar N, et al.
Sci Rep. 2018 Nov 19;8(1):17023. doi: 10.1038/s41598-018-34911-9.
Sci Rep. 2018.
PMID: 30451932
Free PMC article.
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An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy.
Darini C, Ghaddar N, Chabot C, Assaker G, Sabri S, Wang S, Krishnamoorthy J, Buchanan M, Aguilar-Mahecha A, Abdulkarim B, Deschenes J, Torres J, Ursini-Siegel J, Basik M, Koromilas AE.
Darini C, et al. Among authors: ghaddar n.
Nat Commun. 2019 May 13;10(1):2139. doi: 10.1038/s41467-019-10138-8.
Nat Commun. 2019.
PMID: 31086176
Free PMC article.
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Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Krishnamoorthy J, Tenkerian C, Gupta J, Ghaddar N, Wang S, Darini C, Staschke KA, Ghosh A, Gandin V, Topisirovic I, Kristof AS, Hatzoglou M, Simos G, Koromilas AE.
Krishnamoorthy J, et al. Among authors: ghaddar n.
Cell Death Dis. 2018 Feb 15;9(3):254. doi: 10.1038/s41419-018-0326-2.
Cell Death Dis. 2018.
PMID: 29449538
Free PMC article.
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