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Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action.
Di Santo R, Costi R, Roux A, Artico M, Lavecchia A, Marinelli L, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: novellino e. J Med Chem. 2006 Mar 23;49(6):1939-45. doi: 10.1021/jm0511583. J Med Chem. 2006. PMID: 16539381 Free PMC article.
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity.
Regina GL, Coluccia A, Piscitelli F, Bergamini A, Sinistro A, Cavazza A, Maga G, Samuele A, Zanoli S, Novellino E, Artico M, Silvestri R. Regina GL, et al. Among authors: novellino e. J Med Chem. 2007 Oct 4;50(20):5034-8. doi: 10.1021/jm070488f. Epub 2007 Sep 6. J Med Chem. 2007. PMID: 17803291
Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, and biological activities.
Di Santo R, Costi R, Roux A, Miele G, Crucitti GC, Iacovo A, Rosi F, Lavecchia A, Marinelli L, Di Giovanni C, Novellino E, Palmisano L, Andreotti M, Amici R, Galluzzo CM, Nencioni L, Palamara AT, Pommier Y, Marchand C. Di Santo R, et al. Among authors: novellino e. J Med Chem. 2008 Aug 14;51(15):4744-50. doi: 10.1021/jm8001422. Epub 2008 Jul 23. J Med Chem. 2008. PMID: 18646746 Free PMC article.
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: novellino e. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836
739 results