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Casein kinase 2 binds to and phosphorylates BRCA1.
O'Brien KA, Lemke SJ, Cocke KS, Rao RN, Beckmann RP. O'Brien KA, et al. Biochem Biophys Res Commun. 1999 Jul 14;260(3):658-64. doi: 10.1006/bbrc.1999.0892. Biochem Biophys Res Commun. 1999. PMID: 10403822
Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators.
Perry WL 3rd, Shepard RL, Sampath J, Yaden B, Chin WW, Iversen PW, Jin S, Lesoon A, O'Brien KA, Peek VL, Rolfe M, Shyjan A, Tighe M, Williamson M, Krishnan V, Moore RE, Dantzig AH. Perry WL 3rd, et al. Cancer Res. 2005 Aug 1;65(15):6593-600. doi: 10.1158/0008-5472.CAN-03-3675. Cancer Res. 2005. PMID: 16061639
Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders.
Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, Cowan QT, Bruck PT, Mercader K, Alotaibi M, Long T, Hall JE, Moya EA, Bauk MA, Reeves JJ, Kong MC, Salem RM, Vizcardo-Galindo G, Macarlupu JL, Figueroa-Mujíca R, Bermudez D, Corante N, Gaio E, Fox KP, Salomaa V, Havulinna AS, Murray AJ, Malhotra A, Powel FL, Jain M, Komor AC, Cavalleri GL, Huff CD, Villafuerte FC, Simonson TS. Lawrence ES, et al. Among authors: o brien ka. Sci Adv. 2024 Feb 9;10(6):eadj5661. doi: 10.1126/sciadv.adj5661. Epub 2024 Feb 9. Sci Adv. 2024. PMID: 38335297 Free PMC article.
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing.
Zumbrun EE, Garvey CB, Wells JB, Lynn GC, Van Tongeren S, Steffens JT, Wetzel KS, Gomba LM, O'Brien KA, Rossi FD, Zeng X, Lee ED, Raymond JLW, Hoffman DA, Jay AN, Brown ES, Kallgren PA, Norris SL, Cantey-Kiser J, Kudiya H, Arthur C, Blair C, Babusis D, Chu VC, Singh B, Bannister R, Porter DP, Cihlar T, Dye JM. Zumbrun EE, et al. Among authors: o brien ka. Viruses. 2023 Nov 28;15(12):2335. doi: 10.3390/v15122335. Viruses. 2023. PMID: 38140576 Free PMC article.
Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia.
O'Brien KA, Gu W, Houck JA, Holzner LMW, Yung HW, Armstrong JL, Sowton AP, Baxter R, Darwin PM, Toledo-Jaldin L, Lazo-Vega L, Moreno-Aramayo AE, Miranda-Garrido V, Shortt JA, Matarazzo CJ, Yasini H, Burton GJ, Moore LG, Simonson TS, Murray AJ, Julian CG. O'Brien KA, et al. Hypertension. 2024 Feb;81(2):319-329. doi: 10.1161/HYPERTENSIONAHA.123.21748. Epub 2023 Nov 29. Hypertension. 2024. PMID: 38018457
Timing of exercise therapy when initiating adjuvant chemotherapy for breast cancer: a randomized trial.
Scott JM, Lee J, Herndon JE, Michalski MG, Lee CP, O'Brien KA, Sasso JP, Yu AF, Rowed KA, Bromberg JF, Traina TA, Gucalp A, Sanford RA, Gajria D, Modi S, Comen EA, D'Andrea G, Blinder VS, Eves ND, Peppercorn JM, Moskowitz CS, Dang CT, Jones LW. Scott JM, et al. Among authors: o brien ka. Eur Heart J. 2023 Dec 7;44(46):4878-4889. doi: 10.1093/eurheartj/ehad085. Eur Heart J. 2023. PMID: 36806405 Free PMC article. Clinical Trial.
83 results