O'Malley ME - Search Results

1

Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers.

Downs-Canner S, Guo ZS, Ravindranathan R, Breitbach CJ, O'Malley ME, Jones HL, Moon A, McCart JA, Shuai Y, Zeh HJ, Bartlett DL. Downs-Canner S, et al. Among authors: o malley me. Mol Ther. 2016 Aug;24(8):1492-501. doi: 10.1038/mt.2016.101. Epub 2016 May 16. Mol Ther. 2016. PMID: 27203445 Free PMC article. Clinical Trial.

2

Chemokine expression from oncolytic vaccinia virus enhances vaccine therapies of cancer.

Li J, O'Malley M, Urban J, Sampath P, Guo ZS, Kalinski P, Thorne SH, Bartlett DL. Li J, et al. Mol Ther. 2011 Apr;19(4):650-7. doi: 10.1038/mt.2010.312. Epub 2011 Jan 25. Mol Ther. 2011. PMID: 21266959 Free PMC article.

3

A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virus.

Yang S, Guo ZS, O'Malley ME, Yin X, Zeh HJ, Bartlett DL. Yang S, et al. Gene Ther. 2007 Apr;14(8):638-47. doi: 10.1038/sj.gt.3302914. Epub 2007 Feb 1. Gene Ther. 2007. PMID: 17268533

4

Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene.

Chalikonda S, Kivlen MH, O'Malley ME, Eric Dong XD, McCart JA, Gorry MC, Yin XY, Brown CK, Zeh HJ 3rd, Guo ZS, Bartlett DL. Chalikonda S, et al. Cancer Gene Ther. 2008 Feb;15(2):115-25. doi: 10.1038/sj.cgt.7701110. Epub 2007 Dec 14. Cancer Gene Ther. 2008. PMID: 18084242 Free PMC article.

5

TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal cancer.

Ziauddin MF, Guo ZS, O'Malley ME, Austin F, Popovic PJ, Kavanagh MA, Li J, Sathaiah M, Thirunavukarasu P, Fang B, Lee YJ, Bartlett DL. Ziauddin MF, et al. Gene Ther. 2010 Apr;17(4):550-9. doi: 10.1038/gt.2010.5. Epub 2010 Feb 25. Gene Ther. 2010. PMID: 20182517 Free PMC article.

6

The combination of immunosuppression and carrier cells significantly enhances the efficacy of oncolytic poxvirus in the pre-immunized host.

Guo ZS, Parimi V, O'Malley ME, Thirunavukarasu P, Sathaiah M, Austin F, Bartlett DL. Guo ZS, et al. Gene Ther. 2010 Dec;17(12):1465-75. doi: 10.1038/gt.2010.104. Epub 2010 Aug 12. Gene Ther. 2010. PMID: 20703311 Free PMC article.

7

Oncolytic poxvirus armed with Fas ligand leads to induction of cellular Fas receptor and selective viral replication in FasR-negative cancer.

Sathaiah M, Thirunavukkarasu P, O'Malley ME, Kavanagh MA, Ravindranathan R, Austin F, Guo ZS, Bartlett DL. Sathaiah M, et al. Cancer Gene Ther. 2012 Mar;19(3):192-201. doi: 10.1038/cgt.2011.77. Epub 2011 Nov 25. Cancer Gene Ther. 2012. PMID: 22116377 Free PMC article.

8

Inhibitors of C5 complement enhance vaccinia virus oncolysis.

Magge D, Guo ZS, O'Malley ME, Francis L, Ravindranathan R, Bartlett DL. Magge D, et al. Cancer Gene Ther. 2013 Jun;20(6):342-50. doi: 10.1038/cgt.2013.26. Epub 2013 May 10. Cancer Gene Ther. 2013. PMID: 23661042 Free PMC article.

9

A rationally designed A34R mutant oncolytic poxvirus: improved efficacy in peritoneal carcinomatosis.

Thirunavukarasu P, Sathaiah M, Gorry MC, O'Malley ME, Ravindranathan R, Austin F, Thorne SH, Guo ZS, Bartlett DL. Thirunavukarasu P, et al. Mol Ther. 2013 May;21(5):1024-33. doi: 10.1038/mt.2013.27. Epub 2013 Feb 26. Mol Ther. 2013. PMID: 23439499 Free PMC article.

10

First-in-man study of western reserve strain oncolytic vaccinia virus: safety, systemic spread, and antitumor activity.

Zeh HJ, Downs-Canner S, McCart JA, Guo ZS, Rao UN, Ramalingam L, Thorne SH, Jones HL, Kalinski P, Wieckowski E, O'Malley ME, Daneshmand M, Hu K, Bell JC, Hwang TH, Moon A, Breitbach CJ, Kirn DH, Bartlett DL. Zeh HJ, et al. Mol Ther. 2015 Jan;23(1):202-14. doi: 10.1038/mt.2014.194. Epub 2014 Oct 8. Mol Ther. 2015. PMID: 25292189 Free PMC article. Clinical Trial.

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