O'Sullivan RJ - Search Results

1

Telomeres: protecting chromosomes against genome instability.

O'Sullivan RJ, Karlseder J. O'Sullivan RJ, et al. Nat Rev Mol Cell Biol. 2010 Mar;11(3):171-81. doi: 10.1038/nrm2848. Epub 2010 Feb 3. Nat Rev Mol Cell Biol. 2010. PMID: 20125188 Free PMC article. Review.

2

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres.

O'Sullivan RJ, Kubicek S, Schreiber SL, Karlseder J. O'Sullivan RJ, et al. Nat Struct Mol Biol. 2010 Oct;17(10):1218-25. doi: 10.1038/nsmb.1897. Epub 2010 Oct 3. Nat Struct Mol Biol. 2010. PMID: 20890289 Free PMC article.

3

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer.

Corpet A, De Koning L, Toedling J, Savignoni A, Berger F, Lemaître C, O'Sullivan RJ, Karlseder J, Barillot E, Asselain B, Sastre-Garau X, Almouzni G. Corpet A, et al. EMBO J. 2011 Feb 2;30(3):480-93. doi: 10.1038/emboj.2010.335. Epub 2010 Dec 21. EMBO J. 2011. PMID: 21179005 Free PMC article.

4

TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.

Flynn RL, Centore RC, O'Sullivan RJ, Rai R, Tse A, Songyang Z, Chang S, Karlseder J, Zou L. Flynn RL, et al. Nature. 2011 Mar 24;471(7339):532-6. doi: 10.1038/nature09772. Epub 2011 Mar 13. Nature. 2011. PMID: 21399625 Free PMC article.

5

The great unravelling: chromatin as a modulator of the aging process.

O'Sullivan RJ, Karlseder J. O'Sullivan RJ, et al. Trends Biochem Sci. 2012 Nov;37(11):466-76. doi: 10.1016/j.tibs.2012.08.001. Epub 2012 Sep 6. Trends Biochem Sci. 2012. PMID: 22959736 Free PMC article. Review.

6

Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.

O'Sullivan RJ, Arnoult N, Lackner DH, Oganesian L, Haggblom C, Corpet A, Almouzni G, Karlseder J. O'Sullivan RJ, et al. Nat Struct Mol Biol. 2014 Feb;21(2):167-74. doi: 10.1038/nsmb.2754. Epub 2014 Jan 12. Nat Struct Mol Biol. 2014. PMID: 24413054 Free PMC article.

7

Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.

Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Garcia-Exposito L, et al. Cell Rep. 2016 Nov 8;17(7):1858-1871. doi: 10.1016/j.celrep.2016.10.048. Cell Rep. 2016. PMID: 27829156 Free PMC article.

8

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, de Vitis M, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ. Barroso-González J, et al. Mol Cell. 2019 Oct 3;76(1):11-26.e7. doi: 10.1016/j.molcel.2019.06.043. Epub 2019 Aug 7. Mol Cell. 2019. PMID: 31400850 Free PMC article.

9

New twists to the ALTernative endings at telomeres.

Bhargava R, Lynskey ML, O'Sullivan RJ. Bhargava R, et al. Among authors: o sullivan rj. DNA Repair (Amst). 2022 Jul;115:103342. doi: 10.1016/j.dnarep.2022.103342. Epub 2022 May 13. DNA Repair (Amst). 2022. PMID: 35588569 Free PMC article. Review.

10

TZAP-ing telomeres down to size.

Garcia-Exposito L, O'Sullivan RJ. Garcia-Exposito L, et al. EMBO Rep. 2017 Jun;18(6):861-863. doi: 10.15252/embr.201744354. Epub 2017 May 12. EMBO Rep. 2017. PMID: 28500256 Free PMC article.

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