O'connor DT - Search Results

1

Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism.

Le Corre P, Parmer RJ, Kailasam MT, Kennedy BP, Skaar TP, Ho H, Leverge R, Smith DW, Ziegler MG, Insel PA, Schork NJ, Flockhart DA, O'connor DT. Le Corre P, et al. Clin Pharmacol Ther. 2004 Aug;76(2):139-53. doi: 10.1016/j.clpt.2004.04.010. Clin Pharmacol Ther. 2004. PMID: 15289791

2

Human response to alpha2-adrenergic agonist stimulation studied in an isolated vascular bed in vivo: Biphasic influence of dose, age, gender, and receptor genotype.

King D, Etzel JP, Chopra S, Smith J, Cadman PE, Rao F, Funk SD, Rana BK, Schork NJ, Insel PA, O'Connor DT. King D, et al. Clin Pharmacol Ther. 2005 May;77(5):388-403. doi: 10.1016/j.clpt.2005.02.008. Clin Pharmacol Ther. 2005. PMID: 15900285

3

Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response.

Etzel JP, Rana BK, Wen G, Parmer RJ, Schork NJ, O'Connor DT, Insel PA. Etzel JP, et al. Hypertension. 2005 Jun;45(6):1207-13. doi: 10.1161/01.HYP.0000166721.42734.49. Hypertension. 2005. PMID: 15920038

4

Expression of altered alpha2-adrenergic phenotypic traits in normotensive humans at genetic risk of hereditary (essential) hypertension.

Dao TT, Kailasam MT, Parmer RJ, Le HV, Le Verge R, Kennedy BP, Ziegler G, Insel PA, Wright FA, O'Connor DT. Dao TT, et al. J Hypertens. 1998 Jun;16(6):779-92. doi: 10.1097/00004872-199816060-00009. J Hypertens. 1998. PMID: 9663918

5

Variability in phenylephrine response and essential hypertension: a search for human alpha(1B)-adrenergic receptor polymorphisms.

Büscher R, Herrmann V, Ring KM, Kailasam MT, O'Connor DT, Parmer RJ, Insel PA. Büscher R, et al. J Pharmacol Exp Ther. 1999 Nov;291(2):793-8. J Pharmacol Exp Ther. 1999. PMID: 10525102

6

Adrenergic polymorphism and the human stress response.

Rao F, Zhang L, Wessel J, Zhang K, Wen G, Kennedy BP, Rana BK, Das M, Rodriguez-Flores JL, Smith DW, Cadman PE, Salem RM, Mahata SK, Schork NJ, Taupenot L, Ziegler MG, O'Connor DT. Rao F, et al. Ann N Y Acad Sci. 2008 Dec;1148:282-96. doi: 10.1196/annals.1410.085. Ann N Y Acad Sci. 2008. PMID: 19120120 Free PMC article.

7

Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs.

Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, Schork NJ, O'Connor DT, Taylor P. Rana BK, et al. J Pharmacol Exp Ther. 2009 Nov;331(2):419-28. doi: 10.1124/jpet.109.157271. Epub 2009 Aug 11. J Pharmacol Exp Ther. 2009. PMID: 19671882 Free PMC article.

8

Interactive effects of common beta2-adrenoceptor haplotypes and age on susceptibility to hypertension and receptor function.

Bao X, Mills PJ, Rana BK, Dimsdale JE, Schork NJ, Smith DW, Rao F, Milic M, O'Connor DT, Ziegler MG. Bao X, et al. Hypertension. 2005 Aug;46(2):301-7. doi: 10.1161/01.HYP.0000175842.19266.95. Epub 2005 Jul 18. Hypertension. 2005. PMID: 16027244

9

Population-based sample reveals gene-gender interactions in blood pressure in White Americans.

Rana BK, Insel PA, Payne SH, Abel K, Beutler E, Ziegler MG, Schork NJ, O'Connor DT. Rana BK, et al. Hypertension. 2007 Jan;49(1):96-106. doi: 10.1161/01.HYP.0000252029.35106.67. Epub 2006 Dec 11. Hypertension. 2007. PMID: 17159089

10

Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.

O'Connor DT, Kailasam MT, Kennedy BP, Ziegler MG, Yanaihara N, Parmer RJ. O'Connor DT, et al. J Hypertens. 2002 Jul;20(7):1335-45. doi: 10.1097/00004872-200207000-00020. J Hypertens. 2002. PMID: 12131530 Clinical Trial.

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