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Post-translational insertion of boron in proteins to probe and modulate function.
Mollner TA, Isenegger PG, Josephson B, Buchanan C, Lercher L, Oehlrich D, Hansen DF, Mohammed S, Baldwin AJ, Gouverneur V, Davis BG. Mollner TA, et al. Among authors: oehlrich d. Nat Chem Biol. 2021 Dec;17(12):1245-1261. doi: 10.1038/s41589-021-00883-7. Epub 2021 Nov 1. Nat Chem Biol. 2021. PMID: 34725511 Free PMC article.
The Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides.
Richards-Taylor CS, Martínez-Lamenca C, Leenaerts JE, Trabanco AA, Oehlrich D. Richards-Taylor CS, et al. Among authors: oehlrich d. J Org Chem. 2017 Sep 15;82(18):9898-9904. doi: 10.1021/acs.joc.7b01628. Epub 2017 Aug 30. J Org Chem. 2017. PMID: 28809121
A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo.
Peschiulli A, Oehlrich D, Van Gool M, Austin N, Van Brandt S, Surkyn M, De Cleyn M, Vos A, Tresadern G, Rombouts FJR, Macdonald GJ, Moechars D, Trabanco AA, Gijsen HJM. Peschiulli A, et al. Among authors: oehlrich d. ACS Med Chem Lett. 2021 Dec 1;13(1):76-83. doi: 10.1021/acsmedchemlett.1c00445. eCollection 2022 Jan 13. ACS Med Chem Lett. 2021. PMID: 35059126 Free PMC article.
Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads.
Oehlrich D, Peschiulli A, Tresadern G, Van Gool M, Vega JA, De Lucas AI, Alonso de Diego SA, Prokopcova H, Austin N, Van Brandt S, Surkyn M, De Cleyn M, Vos A, Rombouts FJR, Macdonald G, Moechars D, Gijsen HJM, Trabanco AA. Oehlrich D, et al. ACS Med Chem Lett. 2019 Jul 2;10(8):1159-1165. doi: 10.1021/acsmedchemlett.9b00181. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413800 Free PMC article.
39 results