Ofran Y - Search Results

1

Computational Design of Epitope-Specific Functional Antibodies.

Nimrod G, Fischman S, Austin M, Herman A, Keyes F, Leiderman O, Hargreaves D, Strajbl M, Breed J, Klompus S, Minton K, Spooner J, Buchanan A, Vaughan TJ, Ofran Y. Nimrod G, et al. Among authors: ofran y. Cell Rep. 2018 Nov 20;25(8):2121-2131.e5. doi: 10.1016/j.celrep.2018.10.081. Cell Rep. 2018. PMID: 30463010 Free article.

2

Computational design of antibodies.

Fischman S, Ofran Y. Fischman S, et al. Among authors: ofran y. Curr Opin Struct Biol. 2018 Aug;51:156-162. doi: 10.1016/j.sbi.2018.04.007. Epub 2018 May 20. Curr Opin Struct Biol. 2018. PMID: 29791878 Review.

3

Computational identification of antigen-binding antibody fragments.

Burkovitz A, Leiderman O, Sela-Culang I, Byk G, Ofran Y. Burkovitz A, et al. Among authors: ofran y. J Immunol. 2013 Mar 1;190(5):2327-34. doi: 10.4049/jimmunol.1200757. Epub 2013 Jan 28. J Immunol. 2013. PMID: 23359499

4

Using a combined computational-experimental approach to predict antibody-specific B cell epitopes.

Sela-Culang I, Benhnia MR, Matho MH, Kaever T, Maybeno M, Schlossman A, Nimrod G, Li S, Xiang Y, Zajonc D, Crotty S, Ofran Y, Peters B. Sela-Culang I, et al. Among authors: ofran y. Structure. 2014 Apr 8;22(4):646-57. doi: 10.1016/j.str.2014.02.003. Epub 2014 Mar 13. Structure. 2014. PMID: 24631463 Free article.

5

De-novo protein function prediction using DNA binding and RNA binding proteins as a test case.

Peled S, Leiderman O, Charar R, Efroni G, Shav-Tal Y, Ofran Y. Peled S, et al. Among authors: ofran y. Nat Commun. 2016 Nov 21;7:13424. doi: 10.1038/ncomms13424. Nat Commun. 2016. PMID: 27869118 Free PMC article.

6

Antibody specific epitope prediction-emergence of a new paradigm.

Sela-Culang I, Ofran Y, Peters B. Sela-Culang I, et al. Among authors: ofran y. Curr Opin Virol. 2015 Apr;11:98-102. doi: 10.1016/j.coviro.2015.03.012. Epub 2015 Mar 31. Curr Opin Virol. 2015. PMID: 25837466 Free PMC article. Review.

7

The indistinguishability of epitopes from protein surface is explained by the distinct binding preferences of each of the six antigen-binding loops.

Kunik V, Ofran Y. Kunik V, et al. Among authors: ofran y. Protein Eng Des Sel. 2013 Oct;26(10):599-609. doi: 10.1093/protein/gzt027. Epub 2013 Jun 10. Protein Eng Des Sel. 2013. PMID: 23754530

8

Understanding differences between synthetic and natural antibodies can help improve antibody engineering.

Burkovitz A, Ofran Y. Burkovitz A, et al. Among authors: ofran y. MAbs. 2016;8(2):278-87. doi: 10.1080/19420862.2015.1123365. Epub 2015 Dec 14. MAbs. 2016. PMID: 26652053 Free PMC article.

9

Structural consensus among antibodies defines the antigen binding site.

Kunik V, Peters B, Ofran Y. Kunik V, et al. Among authors: ofran y. PLoS Comput Biol. 2012;8(2):e1002388. doi: 10.1371/journal.pcbi.1002388. Epub 2012 Feb 23. PLoS Comput Biol. 2012. PMID: 22383868 Free PMC article.

10

Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein.

Kaever T, Meng X, Matho MH, Schlossman A, Li S, Sela-Culang I, Ofran Y, Buller M, Crump RW, Parker S, Frazier A, Crotty S, Zajonc DM, Peters B, Xiang Y. Kaever T, et al. Among authors: ofran y. J Virol. 2014 Oct;88(19):11339-55. doi: 10.1128/JVI.01491-14. Epub 2014 Jul 16. J Virol. 2014. PMID: 25031354 Free PMC article.

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