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Characterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypes.
Nakamura S, Yamamura Y, Itoh S, Hirano T, Tsujimae K, Aoyama M, Kondo K, Ogawa H, Shinohara T, Kan K, Tanada Y, Teramoto S, Sumida T, Nakayama S, Sekiguchi K, Kambe T, Tsujimoto G, Mori T, Tominaga M. Nakamura S, et al. Among authors: ogawa h. Br J Pharmacol. 2000 Apr;129(8):1700-6. doi: 10.1038/sj.bjp.0703221. Br J Pharmacol. 2000. PMID: 10780976 Free PMC article.
Characterization of orally active nonpeptide vasopressin V(2) receptor agonist. Synthesis and biological evaluation of both the (5R)- and (5S)-enantioisomers of 2-[1-(2-Chloro-4-pyrrolidin-1-yl-benzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepin- 5-yl]-N-isopropylacetamide.
Kondo K, Kan K, Tanada Y, Bando M, Shinohara T, Kurimura M, Ogawa H, Nakamura S, Hirano T, Yamamura Y, Kido M, Mori T, Tominaga M. Kondo K, et al. Among authors: ogawa h. J Med Chem. 2002 Aug 15;45(17):3805-8. doi: 10.1021/jm020133q. J Med Chem. 2002. PMID: 12166952
OPC-41061, a highly potent human vasopressin V2-receptor antagonist: pharmacological profile and aquaretic effect by single and multiple oral dosing in rats.
Yamamura Y, Nakamura S, Itoh S, Hirano T, Onogawa T, Yamashita T, Yamada Y, Tsujimae K, Aoyama M, Kotosai K, Ogawa H, Yamashita H, Kondo K, Tominaga M, Tsujimoto G, Mori T. Yamamura Y, et al. Among authors: ogawa h. J Pharmacol Exp Ther. 1998 Dec;287(3):860-7. J Pharmacol Exp Ther. 1998. PMID: 9864265
7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoyl-amino)benzoyl ]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-41061): a potent, orally active nonpeptide arginine vasopressin V2 receptor antagonist.
Kondo K, Ogawa H, Yamashita H, Miyamoto H, Tanaka M, Nakaya K, Kitano K, Yamamura Y, Nakamura S, Onogawa T, Mori T, Tominaga M. Kondo K, et al. Among authors: ogawa h. Bioorg Med Chem. 1999 Aug;7(8):1743-54. doi: 10.1016/s0968-0896(99)00101-7. Bioorg Med Chem. 1999. PMID: 10482466
5,306 results