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IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody.
Saito S, Sano K, Suzuki T, Ainai A, Taga Y, Ueno T, Tabata K, Saito K, Wada Y, Ohara Y, Takeyama H, Odagiri T, Kageyama T, Ogawa-Goto K, Multihartina P, Setiawaty V, Pangesti KNA, Hasegawa H. Saito S, et al. Among authors: ohara y. PLoS Pathog. 2019 Jan 3;15(1):e1007427. doi: 10.1371/journal.ppat.1007427. eCollection 2019 Jan. PLoS Pathog. 2019. PMID: 30605488 Free PMC article.
Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques.
Chua BY, Sekiya T, Koutsakos M, Nomura N, Rowntree LC, Nguyen THO, McQuilten HA, Ohno M, Ohara Y, Nishimura T, Endo M, Itoh Y, Habel JR, Selva KJ, Wheatley AK, Wines BD, Hogarth PM, Kent SJ, Chung AW, Jackson DC, Brown LE, Shingai M, Kedzierska K, Kida H. Chua BY, et al. Among authors: ohara y. PLoS Pathog. 2022 Oct 7;18(10):e1010891. doi: 10.1371/journal.ppat.1010891. eCollection 2022 Oct. PLoS Pathog. 2022. PMID: 36206307 Free PMC article.
Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays.
Koutsakos M, Sekiya T, Chua BY, Nguyen THO, Wheatley AK, Juno JA, Ohno M, Nomura N, Ohara Y, Nishimura T, Endo M, Suzuki S, Ishigaki H, Nakayama M, Nguyen CT, Itoh Y, Shingai M, Ogasawara K, Kino Y, Kent SJ, Jackson DC, Brown LE, Kida H, Kedzierska K. Koutsakos M, et al. Among authors: ohara y. Immunol Cell Biol. 2021 Jan;99(1):97-106. doi: 10.1111/imcb.12383. Epub 2020 Sep 7. Immunol Cell Biol. 2021. PMID: 32741011
Inactivated whole virus particle vaccine with potent immunogenicity and limited IL-6 induction is ideal for influenza.
Sekiya T, Mifsud EJ, Ohno M, Nomura N, Sasada M, Fujikura D, Daito T, Shingai M, Ohara Y, Nishimura T, Endo M, Mitsumata R, Ikeda T, Hatanaka H, Kitayama H, Motokawa K, Sobue T, Suzuki S, Itoh Y, Brown LE, Ogasawara K, Kino Y, Kida H. Sekiya T, et al. Among authors: ohara y. Vaccine. 2019 Apr 3;37(15):2158-2166. doi: 10.1016/j.vaccine.2019.02.057. Epub 2019 Mar 8. Vaccine. 2019. PMID: 30857932
Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells.
Shingai M, Nomura N, Sekiya T, Ohno M, Fujikura D, Handabile C, Omori R, Ohara Y, Nishimura T, Endo M, Kimachi K, Mitsumata R, Ikeda T, Kitayama H, Hatanaka H, Sobue T, Muro F, Suzuki S, Thanh Nguyen C, Ishigaki H, Nakayama M, Mori Y, Itoh Y, Koutsakos M, Chua BY, Kedzierska K, Brown LE, Jackson DC, Ogasawara K, Kino Y, Kida H. Shingai M, et al. Among authors: ohara y. Vaccine. 2021 Jun 29;39(29):3940-3951. doi: 10.1016/j.vaccine.2021.05.065. Epub 2021 Jun 2. Vaccine. 2021. PMID: 34090697 Free article.
618 results