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Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction.
Okamoto Y, Chaves A, Chen J, Kelley R, Jones K, Weed HG, Gardner KL, Gangi L, Yamaguchi M, Klomkleaw W, Nakayama T, Hamlin RL, Carnes C, Altschuld R, Bauer J, Hai T. Okamoto Y, et al. Am J Pathol. 2001 Aug;159(2):639-50. doi: 10.1016/S0002-9440(10)61735-X. Am J Pathol. 2001. PMID: 11485922 Free PMC article.
The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae.
Vaena de Avalos S, Su X, Zhang M, Okamoto Y, Dowhan W, Hannun YA. Vaena de Avalos S, et al. Among authors: okamoto y. J Biol Chem. 2005 Feb 25;280(8):7170-7. doi: 10.1074/jbc.M411058200. Epub 2004 Dec 15. J Biol Chem. 2005. PMID: 15611094 Free article.
Recently, we reported that Isc1p is post-translationally activated in the post-diauxic phase of growth and that it localizes to mitochondria (Vaena de Avalos, S., Okamoto, Y., and Hannun, Y. A. (2004) J. Biol. Chem. 279, 11537-11545). ...
Recently, we reported that Isc1p is post-translationally activated in the post-diauxic phase of growth and that it localizes to mitochondria …
Functional analysis of ISC1 by site-directed mutagenesis.
Okamoto Y, Vaena de Avalos S, Hannun YA. Okamoto Y, et al. Biochemistry. 2003 Jul 1;42(25):7855-62. doi: 10.1021/bi0341354. Biochemistry. 2003. PMID: 12820895
We previously reported that the yeast Saccharomyces cerevisiae ISC1 gene (Yer019w), which has homology to the bacterial sphingomyelinase gene, encodes inositol phosphosphingolipids-phospholipase C, Isc1p [Sawai, H., Okamoto, Y., Luberto, C., Mao, C., Bielawska, A., …
We previously reported that the yeast Saccharomyces cerevisiae ISC1 gene (Yer019w), which has homology to the bacterial sphingomyelinase gen …
Structural requirements for selective binding of ISC1 to anionic phospholipids.
Okamoto Y, Vaena De Avalos S, Hannun YA. Okamoto Y, et al. J Biol Chem. 2002 Nov 29;277(48):46470-7. doi: 10.1074/jbc.M207779200. Epub 2002 Sep 18. J Biol Chem. 2002. PMID: 12244059 Free article.
Yeast ISC1 (Yer019w) encodes inositolphosphosphingolipid-phospholipase C and is activated by phosphatidylserine (PS) and cardiolipin (CL) (Sawai, H., Okamoto, Y., Lubert, C., Mao, C., Bielawska, A., Domae, M., and Hannun, Y. ...
Yeast ISC1 (Yer019w) encodes inositolphosphosphingolipid-phospholipase C and is activated by phosphatidylserine (PS) and cardiolipin (CL) (S …
3,836 results