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West African Sorghum bicolor leaf sheaths have anti-inflammatory and immune-modulating properties in vitro.
J Med Food. 2013 Mar;16(3):230-8. doi: 10.1089/jmf.2012.0214. Epub 2013 Jan 5.
J Med Food. 2013.
PMID: 23289787
Free PMC article.
Clinical efficacy of a West African sorghum bicolor-based traditional herbal preparation Jobelyn shows increased hemoglobin and CD4+ T-lymphocyte counts in HIV-positive patients.
Ayuba GI, Jensen GS, Benson KF, Okubena AM, Okubena O.
Ayuba GI, et al. Among authors: okubena o.
J Altern Complement Med. 2014 Jan;20(1):53-6. doi: 10.1089/acm.2013.0125. Epub 2013 Nov 27.
J Altern Complement Med. 2014.
PMID: 24283768
Free PMC article.
Clinical Trial.
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Jobelyn® attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice.
Omorogbe O, Ajayi AM, Ben-Azu B, Oghwere EE, Adebesin A, Aderibigbe AO, Okubena O, Umukoro S.
Omorogbe O, et al. Among authors: okubena o.
Biomed Pharmacother. 2018 Feb;98:585-593. doi: 10.1016/j.biopha.2017.12.098. Epub 2017 Dec 27.
Biomed Pharmacother. 2018.
PMID: 29288974
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Pro-inflammatory and toxicological evaluation of Hepacare® in mice.
Adebayo AH, Ashano EE, Yakubu OF, Okubena O.
Adebayo AH, et al. Among authors: okubena o.
J Taibah Univ Med Sci. 2017 Mar 31;12(4):313-323. doi: 10.1016/j.jtumed.2017.02.004. eCollection 2017 Aug.
J Taibah Univ Med Sci. 2017.
PMID: 31435257
Free PMC article.
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Jobelyn® ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-κB signaling pathway.
Umukoro S, Oghwere EE, Ben-Azu B, Owoeye O, Ajayi AM, Omorogbe O, Okubena O.
Umukoro S, et al. Among authors: okubena o.
Pathophysiology. 2019 Mar;26(1):77-88. doi: 10.1016/j.pathophys.2018.10.002. Epub 2018 Oct 28.
Pathophysiology. 2019.
PMID: 30413288
Free article.
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Jobelyn® improves motor dysfunctions induced by haloperidol in mice via neuroprotective mechanisms relating to modulation of cAMP response-element binding protein and mitogen-activated protein kinase.
Umukoro S, Ajayi AM, Ben-Azu B, Ademola AP, Areelu J, Orji C, Okubena O.
Umukoro S, et al. Among authors: okubena o.
Metab Brain Dis. 2023 Oct;38(7):2269-2280. doi: 10.1007/s11011-023-01253-z. Epub 2023 Jun 22.
Metab Brain Dis. 2023.
PMID: 37347426
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