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RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.
Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG. Levantini E, et al. Among authors: okuno y. EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285. EMBO J. 2011. PMID: 21873977 Free PMC article.
Transgenic targeting with regulatory elements of the human CD34 gene.
Radomska HS, Gonzalez DA, Okuno Y, Iwasaki H, Nagy A, Akashi K, Tenen DG, Huettner CS. Radomska HS, et al. Among authors: okuno y. Blood. 2002 Dec 15;100(13):4410-9. doi: 10.1182/blood-2002-02-0355. Epub 2002 Aug 15. Blood. 2002. PMID: 12393582 Free article.
Distal elements are critical for human CD34 expression in vivo.
Okuno Y, Huettner CS, Radomska HS, Petkova V, Iwasaki H, Akashi K, Tenen DG. Okuno Y, et al. Blood. 2002 Dec 15;100(13):4420-6. doi: 10.1182/blood-2002-03-0788. Epub 2002 Aug 22. Blood. 2002. PMID: 12393741 Free article.
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. Huang G, et al. Among authors: okuno y. Nat Genet. 2008 Jan;40(1):51-60. doi: 10.1038/ng.2007.7. Epub 2007 Nov 11. Nat Genet. 2008. PMID: 17994017
Regulation of the PU.1 gene by distal elements.
Li Y, Okuno Y, Zhang P, Radomska HS, Chen H, Iwasaki H, Akashi K, Klemsz MJ, McKercher SR, Maki RA, Tenen DG. Li Y, et al. Among authors: okuno y. Blood. 2001 Nov 15;98(10):2958-65. doi: 10.1182/blood.v98.10.2958. Blood. 2001. PMID: 11698277 Free article.
1,256 results