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B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.
Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R. Qian J, et al. Among authors: oliveira ty. Cell. 2014 Dec 18;159(7):1524-37. doi: 10.1016/j.cell.2014.11.013. Epub 2014 Dec 4. Cell. 2014. PMID: 25483777 Free PMC article.
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R. Hakim O, et al. Among authors: oliveira t. Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909. Nature. 2012. PMID: 22314321 Free PMC article.
Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state.
Meredith MM, Liu K, Kamphorst AO, Idoyaga J, Yamane A, Guermonprez P, Rihn S, Yao KH, Silva IT, Oliveira TY, Skokos D, Casellas R, Nussenzweig MC. Meredith MM, et al. Among authors: oliveira ty. J Exp Med. 2012 Aug 27;209(9):1583-93. doi: 10.1084/jem.20121003. Epub 2012 Jul 30. J Exp Med. 2012. PMID: 22851594 Free PMC article.
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Di Virgilio M, Callen E, Yamane A, Zhang W, Jankovic M, Gitlin AD, Feldhahn N, Resch W, Oliveira TY, Chait BT, Nussenzweig A, Casellas R, Robbiani DF, Nussenzweig MC. Di Virgilio M, et al. Among authors: oliveira ty. Science. 2013 Feb 8;339(6120):711-5. doi: 10.1126/science.1230624. Epub 2013 Jan 10. Science. 2013. PMID: 23306439 Free PMC article.
99 results