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Page 1
Targeting IRE1 with small molecules counteracts progression of atherosclerosis.
Tufanli O, Telkoparan Akillilar P, Acosta-Alvear D, Kocaturk B, Onat UI, Hamid SM, Çimen I, Walter P, Weber C, Erbay E. Tufanli O, et al. Among authors: onat ui. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1395-E1404. doi: 10.1073/pnas.1621188114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137856 Free PMC article.
Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis.
Onat UI, Yildirim AD, Tufanli Ö, Çimen I, Kocatürk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. Onat UI, et al. J Am Coll Cardiol. 2019 Mar 19;73(10):1149-1169. doi: 10.1016/j.jacc.2018.12.055. J Am Coll Cardiol. 2019. PMID: 30871699 Free PMC article.
Double bond configuration of palmitoleate is critical for atheroprotection.
Cimen I, Yildirim Z, Dogan AE, Yildirim AD, Tufanli O, Onat UI, Nguyen U, Watkins SM, Weber C, Erbay E. Cimen I, et al. Among authors: onat ui. Mol Metab. 2019 Oct;28:58-72. doi: 10.1016/j.molmet.2019.08.004. Epub 2019 Aug 7. Mol Metab. 2019. PMID: 31422082 Free PMC article.