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M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza.
Cole SL, Dunning J, Kok WL, Benam KH, Benlahrech A, Repapi E, Martinez FO, Drumright L, Powell TJ, Bennett M, Elderfield R, Thomas C; MOSAIC investigators; Dong T, McCauley J, Liew FY, Taylor S, Zambon M, Barclay W, Cerundolo V, Openshaw PJ, McMichael AJ, Ho LP. Cole SL, et al. Among authors: openshaw pj. JCI Insight. 2017 Apr 6;2(7):e91868. doi: 10.1172/jci.insight.91868. JCI Insight. 2017. PMID: 28405622 Free PMC article.
Development of vaccines against common colds.
Olszewska W, Zambon M, Openshaw PJ. Olszewska W, et al. Among authors: openshaw pj. Br Med Bull. 2002;62:99-111. doi: 10.1093/bmb/62.1.99. Br Med Bull. 2002. PMID: 12176853 Review.
Impact of the 2009 influenza pandemic.
Dunning J, Openshaw PJ. Dunning J, et al. Among authors: openshaw pj. Thorax. 2010 Jun;65(6):471-2. doi: 10.1136/thx.2009.133728. Thorax. 2010. PMID: 20522840 No abstract available.
IFITM3 restricts the morbidity and mortality associated with influenza.
Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, Chin CR, Feeley EM, Sims JS, Adams DJ, Wise HM, Kane L, Goulding D, Digard P, Anttila V, Baillie JK, Walsh TS, Hume DA, Palotie A, Xue Y, Colonna V, Tyler-Smith C, Dunning J, Gordon SB; GenISIS Investigators; MOSAIC Investigators; Smyth RL, Openshaw PJ, Dougan G, Brass AL, Kellam P. Everitt AR, et al. Among authors: openshaw pj. Nature. 2012 Mar 25;484(7395):519-23. doi: 10.1038/nature10921. Nature. 2012. PMID: 22446628 Free PMC article.
Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom.
Elderfield RA, Watson SJ, Godlee A, Adamson WE, Thompson CI, Dunning J, Fernandez-Alonso M, Blumenkrantz D, Hussell T; MOSAIC Investigators; Zambon M, Openshaw P, Kellam P, Barclay WS. Elderfield RA, et al. J Virol. 2014 Nov;88(22):13269-83. doi: 10.1128/JVI.01636-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210166 Free PMC article.
Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus.
Habibi MS, Jozwik A, Makris S, Dunning J, Paras A, DeVincenzo JP, de Haan CA, Wrammert J, Openshaw PJ, Chiu C; Mechanisms of Severe Acute Influenza Consortium Investigators. Habibi MS, et al. Among authors: openshaw pj. Am J Respir Crit Care Med. 2015 May 1;191(9):1040-9. doi: 10.1164/rccm.201412-2256OC. Am J Respir Crit Care Med. 2015. PMID: 25730467 Free PMC article. Clinical Trial.
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ, Moffatt MF, O'Garra A, Openshaw PJM; MOSAIC Investigators. Dunning J, et al. Nat Immunol. 2018 Jun;19(6):625-635. doi: 10.1038/s41590-018-0111-5. Epub 2018 May 18. Nat Immunol. 2018. PMID: 29777224 Free PMC article.
305 results