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Safe and Efficient Gene Therapy for Pyruvate Kinase Deficiency.
Garcia-Gomez M, Calabria A, Garcia-Bravo M, Benedicenti F, Kosinski P, López-Manzaneda S, Hill C, Del Mar Mañu-Pereira M, Martín MA, Orman I, Vives-Corrons JL, Kung C, Schambach A, Jin S, Bueren JA, Montini E, Navarro S, Segovia JC. Garcia-Gomez M, et al. Among authors: orman i. Mol Ther. 2016 Aug;24(7):1187-98. doi: 10.1038/mt.2016.87. Epub 2016 May 3. Mol Ther. 2016. PMID: 27138040 Free PMC article.
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Garate Z, Quintana-Bustamante O, Crane AM, Olivier E, Poirot L, Galetto R, Kosinski P, Hill C, Kung C, Agirre X, Orman I, Cerrato L, Alberquilla O, Rodriguez-Fornes F, Fusaki N, Garcia-Sanchez F, Maia TM, Ribeiro ML, Sevilla J, Prosper F, Jin S, Mountford J, Guenechea G, Gouble A, Bueren JA, Davis BR, Segovia JC. Garate Z, et al. Among authors: orman i. Stem Cell Reports. 2015 Dec 8;5(6):1053-1066. doi: 10.1016/j.stemcr.2015.10.002. Epub 2015 Nov 5. Stem Cell Reports. 2015. PMID: 26549847 Free PMC article.
Natural estrogens enhance the engraftment of human hematopoietic stem and progenitor cells in immunodeficient mice.
Fañanas-Baquero S, Orman I, Becerra Aparicio F, Bermudez de Miguel S, Garcia Merino J, Yañez R, Fernandez Sainz Y, Sánchez R, Dessy-Rodríguez M, Alberquilla O, Alfaro D, Zapata A, Bueren JA, Segovia JC, Quintana-Bustamante O. Fañanas-Baquero S, et al. Among authors: orman i. Haematologica. 2021 Jun 1;106(6):1659-1670. doi: 10.3324/haematol.2019.233924. Haematologica. 2021. PMID: 32354868 Free PMC article.
Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice.
Guillén N, Acín S, Navarro MA, Perona JS, Arbonés-Mainar JM, Arnal C, Sarría AJ, Surra JC, Carnicer R, Orman I, Segovia JC, Ruiz-Gutiérrez V, Osada J. Guillén N, et al. Among authors: orman i. Atherosclerosis. 2008 Mar;197(1):72-83. doi: 10.1016/j.atherosclerosis.2007.08.008. Epub 2007 Sep 12. Atherosclerosis. 2008. PMID: 17854812
13 results