Ormsby AR[Author] - Search Results

Year	Number of Results
2012	1
2013	2
2015	1
2017	3
2018	2
2020	3
2022	4
2023	1
2024	0

1

Sequence grammar underlying the unfolding and phase separation of globular proteins.

Ruff KM, Choi YH, Cox D, Ormsby AR, Myung Y, Ascher DB, Radford SE, Pappu RV, Hatters DM. Ruff KM, et al. Among authors: ormsby ar. Mol Cell. 2022 Sep 1;82(17):3193-3208.e8. doi: 10.1016/j.molcel.2022.06.024. Epub 2022 Jul 18. Mol Cell. 2022. PMID: 35853451 Free PMC article.

2

A biosensor-based framework to measure latent proteostasis capacity.

Wood RJ, Ormsby AR, Radwan M, Cox D, Sharma A, Vöpel T, Ebbinghaus S, Oliveberg M, Reid GE, Dickson A, Hatters DM. Wood RJ, et al. Among authors: ormsby ar. Nat Commun. 2018 Jan 18;9(1):287. doi: 10.1038/s41467-017-02562-5. Nat Commun. 2018. PMID: 29348634 Free PMC article.

3

Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli.

Cox D, Ormsby AR, Reid GE, Hatters DM. Cox D, et al. Among authors: ormsby ar. NPJ Syst Biol Appl. 2022 Nov 28;8(1):46. doi: 10.1038/s41540-022-00256-3. NPJ Syst Biol Appl. 2022. PMID: 36443335 Free PMC article.

4

Arginine-rich C9ORF72 ALS proteins stall ribosomes in a manner distinct from a canonical ribosome-associated quality control substrate.

Kriachkov V, Ormsby AR, Kusnadi EP, McWilliam HEG, Mintern JD, Amarasinghe SL, Ritchie ME, Furic L, Hatters DM. Kriachkov V, et al. Among authors: ormsby ar. J Biol Chem. 2023 Jan;299(1):102774. doi: 10.1016/j.jbc.2022.102774. Epub 2022 Dec 5. J Biol Chem. 2023. PMID: 36481270 Free PMC article.

5

A biosensor of protein foldedness identifies increased "holdase" activity of chaperones in the nucleus following increased cytosolic protein aggregation.

Raeburn CB, Ormsby AR, Cox D, Gerak CA, Makhoul C, Moily NS, Ebbinghaus S, Dickson A, McColl G, Hatters DM. Raeburn CB, et al. Among authors: ormsby ar. J Biol Chem. 2022 Aug;298(8):102158. doi: 10.1016/j.jbc.2022.102158. Epub 2022 Jun 17. J Biol Chem. 2022. PMID: 35724963 Free PMC article.

6

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity.

Radwan M, Ang CS, Ormsby AR, Cox D, Daly JC, Reid GE, Hatters DM. Radwan M, et al. Among authors: ormsby ar. Mol Cell Proteomics. 2020 Apr;19(4):640-654. doi: 10.1074/mcp.RA119.001888. Epub 2020 Feb 21. Mol Cell Proteomics. 2020. PMID: 32086375 Free PMC article.

7

Widespread remodeling of proteome solubility in response to different protein homeostasis stresses.

Sui X, Pires DEV, Ormsby AR, Cox D, Nie S, Vecchi G, Vendruscolo M, Ascher DB, Reid GE, Hatters DM. Sui X, et al. Among authors: ormsby ar. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2422-2431. doi: 10.1073/pnas.1912897117. Epub 2020 Jan 21. Proc Natl Acad Sci U S A. 2020. PMID: 31964829 Free PMC article.

8

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis.

Ramdzan YM, Trubetskov MM, Ormsby AR, Newcombe EA, Sui X, Tobin MJ, Bongiovanni MN, Gras SL, Dewson G, Miller JML, Finkbeiner S, Moily NS, Niclis J, Parish CL, Purcell AW, Baker MJ, Wilce JA, Waris S, Stojanovski D, Böcking T, Ang CS, Ascher DB, Reid GE, Hatters DM. Ramdzan YM, et al. Among authors: ormsby ar. Cell Rep. 2017 May 2;19(5):919-927. doi: 10.1016/j.celrep.2017.04.029. Cell Rep. 2017. PMID: 28467905 Free article.

9

Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation.

Polling S, Ormsby AR, Wood RJ, Lee K, Shoubridge C, Hughes JN, Thomas PQ, Griffin MD, Hill AF, Bowden Q, Böcking T, Hatters DM. Polling S, et al. Among authors: ormsby ar. Nat Struct Mol Biol. 2015 Dec;22(12):1008-15. doi: 10.1038/nsmb.3127. Epub 2015 Nov 16. Nat Struct Mol Biol. 2015. PMID: 26571108

10

Tracking protein aggregation and mislocalization in cells with flow cytometry.

Ramdzan YM, Polling S, Chia CP, Ng IH, Ormsby AR, Croft NP, Purcell AW, Bogoyevitch MA, Ng DC, Gleeson PA, Hatters DM. Ramdzan YM, et al. Among authors: ormsby ar. Nat Methods. 2012 Mar 18;9(5):467-70. doi: 10.1038/nmeth.1930. Nat Methods. 2012. PMID: 22426490

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