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Page 1
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H. Magupalli VG, et al. Among authors: orning p. Science. 2020 Sep 18;369(6510):eaas8995. doi: 10.1126/science.aas8995. Science. 2020. PMID: 32943500 Free PMC article.
RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis.
Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, LaMorte M, Gruber R, Keane A, Loring P, Guo L, Xia TH, Zhang B, Orning P, Lien E, Degterev A, Hammond T, Ofengeim D. Zelic M, et al. Among authors: orning p. Cell Rep. 2021 May 11;35(6):109112. doi: 10.1016/j.celrep.2021.109112. Cell Rep. 2021. PMID: 33979622 Free PMC article.
Gasdermins and their role in immunity and inflammation.
Orning P, Lien E, Fitzgerald KA. Orning P, et al. J Exp Med. 2019 Nov 4;216(11):2453-2465. doi: 10.1084/jem.20190545. Epub 2019 Sep 23. J Exp Med. 2019. PMID: 31548300 Free PMC article. Review.
A Sugar Rush for Innate Immunity.
Orning P, Flo TH, Lien E. Orning P, et al. Cell Host Microbe. 2018 Oct 10;24(4):461-463. doi: 10.1016/j.chom.2018.09.017. Cell Host Microbe. 2018. PMID: 30308148 Free PMC article.
Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Nilsen KE, Zhang B, Skjesol A, Ryan L, Vagle H, Bøe MH, Orning P, Kim H, Bakke SS, Elamurugan K, Mestvedt IB, Stenvik J, Husebye H, Lien E, Espevik T, Yurchenko M. Nilsen KE, et al. Among authors: orning p. Life Sci Alliance. 2023 Oct 3;6(12):e202302164. doi: 10.26508/lsa.202302164. Print 2023 Dec. Life Sci Alliance. 2023. PMID: 37788908 Free PMC article.
Streptolysin O Induces the Ubiquitination and Degradation of Pro-IL-1β.
Hancz D, Westerlund E, Valfridsson C, Aemero GM, Bastiat-Sempe B, Orning P, Lien E, Wessels MR, Persson JJ. Hancz D, et al. Among authors: orning p. J Innate Immun. 2019;11(6):457-468. doi: 10.1159/000496403. Epub 2019 Mar 19. J Innate Immun. 2019. PMID: 30889575 Free PMC article.
12 results